Three-hit concept of vulnerability and resilience Flashcards
What are the three hit concepts of vulnerability and resilience?
1: genetic predisposition,
2: early-life environment
3: later-life environment
how does the Three hit concept of vulnerability and resilience work?
Multi-genic inputs (hit-1) interact with early-life environmental inputs and experience-related factors (hit-2), programming phenotypes with differential susceptibility to later-life challenges (hit-3)
The three-hit concept is fundamental for
understanding how individuals can either be prepared for coping with life to come and remain resilient or are unable to do so and succumb to a stress-related mental disorder, under seemingly identical circumstances.
According to the cumulative stress model:
According to the mismatch model