Thought Disorders Flashcards

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1
Q

What are the characteristics of a thought disorder?

A
  • Disorganized Thoughts
  • Hallucinations or Delusions
  • Loss of the self, physical and mental boundaries, i.e. not sure where I stop and you begin
  • Gross impairment of reality testing
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2
Q

What three mental status exam findings will be most often abnormal in people with a thought disorder?

A
  • thought process (disorganization, loose associations)
  • throught content (delusion)
  • perceptions (hallucinations)
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3
Q

What is the prototypic thought disorder?

A

Schizophrenia

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4
Q

What are the NT’s involved in thought disorders?

A
  • Dopamine

- glutamate

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5
Q

What qualify as psychotic symptoms (for schizophrenia) in the DSM?

A
  • Hallucinations
  • delusions
  • disorganized speech
  • grossly disorganized/catatonic behavior
  • Negative symptoms (flat/inppt affect, alogia, avolition)
  • need at least 2, one of which is one of the top 3.
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6
Q

What are the exclusion criteria for schizophrenia?

A
  • No mood symptoms that predominate
  • No medical causes
  • Not induced by a substance
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7
Q

What are positive symptoms?

A

-Hallucinations, delusions, and disorganized behavior are often called the positive symptoms of schizophrenia.

(not a DSM term)

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8
Q

What is one of the most important questions to ask a schizophrenic patient?

A

Whether or not there are thoughts being put in their head.

=Thought insertion

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9
Q

What are negative symptoms?

A
  • Isolation
  • Withdrawal
  • Poor hygiene
  • Flat Affect
  • Lack of Initiative
  • Lack of Interest
  • Lack of Energy
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10
Q

How long must you have active symptoms to be diagnosed with schizophrenia?

A

-one month

**(at least six months for other negative/prodromal symptoms)

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11
Q

What does paranoid schizophrenia entail?

A

-Preoccupation with one or more delusions or frequent auditory hallucinations

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12
Q

What does catatonic schizophrenia entail?

A
  • Not really specific to schizophrenia anymore –now a specifier for any psychiatric illness where catatonia is present
  • motoric immobility
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13
Q

What does residual type schizophrenia entail?

A
  • Absence of prominent delusions, hallucinations, disorganized speech, and grossly disorganized or catatonic behavior (after initial diagnosis of schizo)
  • event with treatment, schizophrenic patients never return to baseline function
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14
Q

What is important about a thought disorder due to a general medical condition?

A

THOUGHT DISORDER MUST BE CAUSED BY THE MEDICAL CONDITION ITSELF

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15
Q

What medications can result in thought disorder symptoms or psychotic symptoms?

A
  • Steroids
  • Interferons
  • Anticholinergics
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16
Q

How does schizophreniform disorder differ from schizophrenia?

A
  1. Total duration of illness (including prodromal, active, and residual) lasts at least one month but less than 6 months (1/3 return to baseline functioning, 2/3 progress to schizophrenia)
  2. Impaired social and occupational functioning during some part of the illness is NOT required
17
Q

What is brief psychotic disorder?

A
  • Sudden onset of schizophrenia symptoms
  • lasts at least one day but less than one month of sx’s
  • return back to premorbid functioning
18
Q

What is delusional disorder?

A
  • one more more bizarre or non-bizarre delusions that persists for at least one month
  • functioning not markedly impaired
19
Q

What does schizoaffective disorder entail?

A
  • Disorder with major mood symptoms (depressed or manic) with concurrent psychotic symptoms
  • equal presence/severity of both
20
Q

Which pathway is probably most important in auditory hallucinations and delusions?

A
  • OVERACTIVITY in Mesolimbic pathway

- Dopamine!

21
Q

Which pathway is probably most important in the negative symptoms and cognitive changes in schizophrenia?

A
  • UNDERACTIVITY in mesocortical pathway

- Dopamine!

22
Q

What is the evidence that glutamate plays a role in thought disorders?

A

-LSD and PCP produce psychosis

23
Q

What brain abnormalities are seen in schizophrenia?

A
  • Ventriculomegaly and temporal lobe volume decrease
  • No gliosis (post natal brain injury)
  • abnormal neural migration