Antidepressants Flashcards
1
Q
What three neurotransmitters are involved in depression?
A
- Serotonin
- Norepinephrine
- Dopamine
2
Q
The __________ has long been implicated in the structural neuropathology of depression and response to stress.
A
hippocampus
3
Q
Depression is associated with hippocampal _______.
A
atrophy
4
Q
Atrophy of the ________ correlates with the duration of depression.
A
Hippocampus
5
Q
Emerging data correlates remission of depression with restoration of normal _______ volume
A
hippocampal
6
Q
What is the only SRI with a really long half life (2-3 days)?
A
Fluoxetine (Prozac)
7
Q
What are the indications for ECT?
A
- Major depressive disorder
- Manic episodes
- Malignant catatonia (schizophrenia)
**chronic schizophrenia is not treated
