Thompson 5 Flashcards

0
Q

Fructose to Fructose 1 P

A

Fructokinase.

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1
Q

Fructose is primarily digested in the _____.

A

liver.

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2
Q

Fructose 1 P to Glyceraldehyde and DHAP.

A

Aldolase B.

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3
Q

Essential fructosuria is a deficiency in ______.

A

fructokinase.

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4
Q

Hereditary fructose intolerance is a deficiency in ____.

A

Aldolase B.

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5
Q

Fructose can be synthesized from ____, a sugar alcohol of glucose, in the seminal vesicles and other tissues.

A

Sorbitol

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6
Q

Elevated levels of _____ in DM and ______ in galactosemia contribute to cataract formation

A

sorbitol, galactitol

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7
Q

UDP glucose can be converted into _________, making bilirubin and xenobiotic compounds more water soluble.

A

UDP glucuronate.

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8
Q

Classical galatosemia is a deficiency in ______.

A

galactosyl uridylyltransferase, galactose 1 P to glucose 1 P. accumulate galactose 1 phosphate and inhibit glycogen metabolism

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9
Q

Nonclassical galactosemia is a defiency in

A

Galactokinase

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10
Q

T or F. UDP glucose can be oxidized to UDP glucuronate, or epimerized to UDP galactose, a precursor to lactate.

A

True.

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11
Q

What comprises the general unit of a glycosaminoglycan?

A

acidic sugar (COOH) with N acetylated amino sugar

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12
Q

What does hyaluronic acid (a glycosaminoglycan) do?

A

cell migration in embryogenesis, morphogenesis, wound healing

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13
Q

What does chondroitin sulfate do?

A

forms bone cartilage cornea.

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14
Q

Keratan sulfate. wat it do

A

transparency of cornea

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15
Q

What does heparin do?

A

anticoagulant. causes release of lipoprotein lipases from capillary walls.

16
Q

What does dermatan sulfate do?>

A

transparency of cornea too, (like keratan sulfate)

binds ldl on plasma walls

17
Q

What does heparan sulfate do?

A

cell surface of skin fibroblasts and aortic wall