Third to 8th weeks Development Flashcards
What does the ectoderm form?
CNS/PNS
sensory epithelium
epidermis
glands and teeth enamel
What induces neurulation?
the appearance of the notochord and the prechordal mesoderm causes the ectoderm to form the neural plate
What is the process of neurulation?
neural folds become elevated and grow toward each other and fuse at midline; the fusion proceeds cranially and caudally and forms the neural tube that stays open until days 25 and 27
How is the neural crest formed?
cells on the lateral edges of the neural plate dissociate and undergo an epithelial-to-mesenchymal transition as they leave the neuroectoderm by active migration
What induces neural crest formation?
BMP
What do neural crest cells form?
connective tissue and bones of face/skull cranial nerve ganglia C cells of the thyroid gland Conotruncal septum of the heart Odontoblasts dermis in face/neck dorsal root ganglia sympathetic chain ganglia/ preaortic ganglia parasympathetic ganglia of the GI tract adrenal medulla schwann cells glial cells meniges of the forebrain melanocytes smooth muscle cells of blood vessels in face/forebrain
What does the somatic/parietal mesoderm form?
lateral and ventral body wall, membranes that line pleural, pericardial, and peritoneal cavities
What doe the splanchnic/visceral mesoderm form?
wall of the gut
What does the intermediate mesoderm form?
urogenital structures
What does the paraxial mesoderm become?
somites, vertebrae, ribs, muscles, and dermis
What is vasculogenesis?
Where vessels arise from blood islands
What is angiogenesis?
where vessels arise by sprouting from existing vessels
What are hemangioblasts?
precursor cells (from mesoderm) for vessel and blood cell formation that are induced by vascular endothelial growth factor (VEGF)
What is the main thing derived from the endoderm layer?
GI tract (folding) but also: epithelial lining of the respiratory tract, urinary bladder, tympanic cavity, and auditory tube, parenchyma of the thyroid, parathyroids, liver, and pancreas, and reticular stroma of the tonsils and thymus
What is the vitelline duct?
how the midgut temporarilly communicates with the yolk sac