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Cell Bio block 1 > Connective Tissue > Flashcards

Connective Tissue Flashcards

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Biology 101 flashcards
1
Q

What do matrix producing cells do?

A

originate locally and stay in the tissue

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2
Q

What do fixed/intrinsic cells do?

A

originate from hematopoietic cells then migrate to the connective tissue where they remain (defensive)

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3
Q

What do wandering cells do?

A

wander in, stay for a short time, then leave or die (defensive)

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4
Q

What are the functions of macrophages?

A

antigen presenting, enhanced immune mediated phagocytosis, tumor resistance, secrete enzymes and cytokines

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5
Q

What are the major components of basophilic granules?

A

histamine and heparin

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6
Q

What do plasma cells do?

A

synthesize and secrete Ig with single specificity

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7
Q

What are adipocytes

A

specialized cells for the storage of neutral fats

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8
Q

What is type 1 collagen?

A

90% of body collagen
found in fibrous supporting tissue
resistant to force, tension, and stretch

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9
Q

what is type 2 collagen?

A

found in cartilage

resistant to pressure

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10
Q

What is type 3 collagen?

A

found in reticular fibers

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11
Q

What is type 4 collagen?

A

found in basement membranes (mesh-like)

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12
Q

What is type 7 collagen?

A

found in anchoring fibrils

linked to basement membrane

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13
Q

What is the basic protein unit of fibrillar collagen?

A

Tropocollagen (glycine + proline + hydroxyproline)

This aggregates to form fibrils w/ cross striations

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14
Q

what type of collagen are reticular fibers?

A

type 3

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15
Q

what are the 2 structural elements of elastic fibers?

A

core of elastin (rich in glycine and proline) and network of fibrillin microfibrils

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16
Q

What does ground substance do?

A

highly hydrated substance that fills the void b/w cells and fibers

17
Q

What are the 3 main classes of ground substance?

A

glycosaminoglycans (GAG)
Proteoglycans
multiadhesive glycoproteins

18
Q

How is hyaluronan different from the other 7 families of GAG’s?

A

extremely long
synthesized on the cell surface
no sulfate
always a free carbohydrate chain (no proteoglycan)

19
Q

What does fibronectin do?

A

It is a multiadhesive ground substance glycoprotein that helps mediate normal cell adhesion and migration and serves as binding site

20
Q

What does laminin do?

A

It is a multiadhesive ground substance glycoprotein that helps in adhesion of epithelial cells to the basal lamina

Cell Bio block 1 (11 decks)

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