Cell Cytoplasm/Organelles Flashcards
What do lipid rafts do?
control movement and distribution of proteins w/in the lipid bilayer
What do pumps transport?
ion
What do channels transport?
ions, molecules, and water in BOTH directions (Ex: Gap junctions)
What is pinocytosis?
cell drinking
What is Tay Sach’s Disease?
Lysosomal disease
deficiency in Beta-hexosaminidas
CHERRY RED SPOT IN RETINA
What is Gaucher disease?
Lysomal disease
defective glucocerebrosidase
treated w/ enzyme replacement
What type of diseases are Hunter and Pompe disease?
Lysosomal
What is the smooth ER involved in?
steroid and glycogen metabolism
membrane formation
detoxing
taking in calcium
What is I-cell disease?
Golgi apparatus disease
rare deficiency of phosphotransferase so lysosomes are empty and cells show large inclusions
What is special about mitochondria characteristically?
they are inherited from mother ONLY
have a double membrane
own circular DNA
produce ATP (ATP synthase in membrane)
What is myoclonic epilepsy with ragged red fibers?
Mitochondrial disorder
ragged muscle fibers due to abnormal mitochon.
cardiac and resp failure
What is Leber’s hereditary optic neuropathy?
Mitochondrial disorder
sudden loss of vision in 2nd-3rd decade
mostly males
What organelle can male infertility be caused from?
Mitochondria
What is Pearson marrow-pancreas syndrome?
Mitochondrial disorder
Anemia and myopathy in childhood
What are the key symptoms of lysosomal diseases?
children loose attained skills
enlarged organs
mental retardation/ behavioral problems