Cell Cytoplasm/Organelles Flashcards

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1
Q

What do lipid rafts do?

A

control movement and distribution of proteins w/in the lipid bilayer

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2
Q

What do pumps transport?

A

ion

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3
Q

What do channels transport?

A

ions, molecules, and water in BOTH directions (Ex: Gap junctions)

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4
Q

What is pinocytosis?

A

cell drinking

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5
Q

What is Tay Sach’s Disease?

A

Lysosomal disease
deficiency in Beta-hexosaminidas
CHERRY RED SPOT IN RETINA

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6
Q

What is Gaucher disease?

A

Lysomal disease
defective glucocerebrosidase
treated w/ enzyme replacement

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7
Q

What type of diseases are Hunter and Pompe disease?

A

Lysosomal

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8
Q

What is the smooth ER involved in?

A

steroid and glycogen metabolism
membrane formation
detoxing
taking in calcium

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9
Q

What is I-cell disease?

A

Golgi apparatus disease

rare deficiency of phosphotransferase so lysosomes are empty and cells show large inclusions

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10
Q

What is special about mitochondria characteristically?

A

they are inherited from mother ONLY
have a double membrane
own circular DNA
produce ATP (ATP synthase in membrane)

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11
Q

What is myoclonic epilepsy with ragged red fibers?

A

Mitochondrial disorder
ragged muscle fibers due to abnormal mitochon.
cardiac and resp failure

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12
Q

What is Leber’s hereditary optic neuropathy?

A

Mitochondrial disorder
sudden loss of vision in 2nd-3rd decade
mostly males

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13
Q

What organelle can male infertility be caused from?

A

Mitochondria

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14
Q

What is Pearson marrow-pancreas syndrome?

A

Mitochondrial disorder

Anemia and myopathy in childhood

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15
Q

What are the key symptoms of lysosomal diseases?

A

children loose attained skills
enlarged organs
mental retardation/ behavioral problems

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16
Q

What do peroxisomes do?

A

In the liver they detox alcohol

they contain hydrogen peroxide that oxidizes organic substances and also catalase to break down the hydrogen peroxide

17
Q

What is Zellwegger syndrome?

A

Peroxisomal disease
absense or reduction of peroxisomes in the kidney and brain due to mutation in PXRI
affects myelin formation in axons
LETHAL

18
Q

What do actin filaments, microtubules, and intermediate filaments do?

A

Actin: anchors, moves proteins, and forms microvilli
Microtubules: move organelles
intermediate: support

19
Q

What is Kartagener’s syndrome?

A

Defects in microtubules
respiratory, reproductive systems affected
situs inversus can be seen