Things to REMEMBER

Question 1

Protein Synthesis inhibitors

Answer 1

Aminoglycosides
Macrolides
Tetracyclines

Question 2

Cell wall synth inhibitors

Answer 2

Cephalosporins
Isoniazid
Penicillins
Vancomycin

Question 3

DNA synth inhibitors

Answer 3

Fluoroquinolones

Question 4

Antimetabolites

Answer 4

Sulfonamides

Question 5

Acquired resistance

Answer 5

Mutation occurs

• Antibiotic destroys sensitive bacteria
• Insensitive mutated bacteria remain and multiply into resistant strain

Question 6

Parenteral Admin Antibiotics

Answer 6

Observe closely for possible allergic reactions after PARENTERAL ADMINISTRATION of antibiotics

Question 7

Claforan

Answer 7

Cephalosporin

Broad spectrum activity against gram-negative organisms
USed For:
Lower respiratory, CNS, GU, bones, and blood

Question 8

Tetracyclines

Answer 8

Effective against broad range of gram + and negative

Decrease effectiveness of oral contraceptives

Use caution in clients w/ impaired kidney or liver function

Do not take with other minerals

Question 9

Fluoroquinolones

Answer 9

All have activity against gram-negative pathogens
-Respiratory system, GI and GU

Monitor WBC / Liver and renal dysfunction

Photophobia / Tendon Rupture in children

Dysrhythmias and liver failure

Question 10

Sulfonamide Adverse

Answer 10

Agranulocytosis

Thrombocytopenia