Therapy for non-endocrine diseases

Question 1

rheumatoid arthritis

Answer 1

initially prednisone, then if necessary use methylprednisone or triamcinolone acetonide (intra-articular injection)

Question 2

OA

Answer 2

direct injection, not first line therapy

Question 3

allergies

Answer 3

in severe cases methyl-prednisolone IV

Question 4

asthma/COPD

Answer 4

fluticasone (meterdose inhaler)
severe attack IV methylprednisolone
safe in children

Question 5

edema

Answer 5

due to ischemia or intracranial tumors = large dose dexamethasone

Question 6

immunosuppression

Answer 6

prednisone high dose

Question 7

infectious diseases

Answer 7

PCP in AIDS patients to suppress inflammation from obstructing airways

Question 8

ocular diseasae

Answer 8

dexamethasone topical, prednisone systemically

Question 9

cancer

Answer 9

any of them

Question 10

rashes, eczema esp

Answer 10

hydrocortisone, triamcinolone

Question 11

diagnostic applications

Answer 11

cushings -> failure of a dexamethasone suppression test

Question 12

contraindications

Answer 12

infections, TB (prevents granuloma)

Question 13

side effects and toxicity

Answer 13

brief - none
prolonged - hyperG, T2DM, HyperT, immunosuppression, myopathy, behavior, cataracts, osteoporosis, growth retardation and obesity
when stopped HPA failure