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809 > MC action > Flashcards

MC action Flashcards

1
Q

aldo’s effect on apical cell membrane of CCD how?

A

ENaC channel up reg by affecting SGK1

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2
Q

aldo’s effect on the basolateral side of the CCD

A

Na/K-ATPase

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3
Q

what are the circulating levels of cortisol and MC?

A

cortisol:aldo=100:1

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4
Q

what effects does this have in the brain? kidney?

A

brain is activated all the time; in the kidney the enzyme 11B-HSD2 converts cortisol -> cortisone (aldo is not sensitive to this)

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809 (8 decks)

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