therapuetic antibodies Flashcards
1
Q
alemtuzumab
A
cd52 –> CLL, MS
2
Q
bevacizumab
A
VEGF
colorectal cancer, renal cell
can cause hemorage, wet macular degen and GI perf
(bev cutting veggies)
3
Q
cetuximab
A
EGFR, tyrosine kinase
think of elephant trunk as colon –> treats stage IV colon cancer
think of giraffe for head and neck cancer
4
Q
rituximab
A
cd20 –> blood cancers
5
Q
trastuzumab
A
her2neu
t-egfr
tyrosine kinase
6
Q
adalimnumab, certolizumba, infliximab
A
soluble TNFa
IBD, rhematoid arthritis, anky, psoriasis
7
Q
is enteracept an anti TNFa ab?
A
No, its a decoy receptor
8
Q
ecluzimab
A
C5
paroxysmal nocturnal hemoglobinuria
9
Q
natalizumba
A
a4 integrin
MS, chrons
10
Q
abciximab
A
anti IIb/IIIa
11
Q
denosumab
A
RANLK
inhibits osteoCLASTS
12
Q
omalizumab
A
IgE –> asthma
13
Q
palivizumab
A
RSV F protein
for kids!!!
