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Step 1 (Molly) > platelet disorders quick reference > Flashcards

platelet disorders quick reference Flashcards

1
Q

bernard soulier

A

low GpIb –> vwf-plt

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2
Q

glanzmann thrombasthenia

A

low GpIIb/IIIa –> plt-plt

no clumping on smear

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3
Q

hemolytic uremic syndrome

A

thrombocytopenia, microangiopathi memmolytic aemia, acute reanal fialure

tx: plasmapheresis

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4
Q

immune thrombocytopenia

A

ANTI-gpbII/IIIa –> splenic consumption

smear: increase megas
tx: IVIG, splenectomy, steroids

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5
Q

thrombotic thromocytopenic purpura

A

problem with ADAMTS13 –> can’t cleave vWF multimers
thrombosis
labs: schistocytes, increase LDH
dx= fever, malaise, microangiopathic hemolytic anemia, thrombocyto
tx= plasmapheresis

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Step 1 (Molly) (30 decks)

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