Therapeutics Flashcards

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1
Q

What are the advantages of topical skin therapeutics?

A

Direct application

Reduced systemic effects

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2
Q

What are the disadvantages of topical treatments?

A

Time consuming
Correct dosage can be difficult
Messy to use

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3
Q

What are gels?

A

Thickened aqueous lotions

Semi-solids containing high molecular weight polymers

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4
Q

What areas of the body are gels mostly used for?

A

Scalp

Hair bearing areas around the face

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5
Q

What are creams?

A

Semi-solid emulsion of oil in water

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6
Q

What do creams contain?

A

Emulsifier and preservative

High water content

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7
Q

What are the benefits of creams?

A

Cools and moisturises
Easy to apply
Non-greasy
Cosmetically acceptable

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8
Q

What are ointments?

A

Semi-solid grease/oil

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9
Q

What do ointments contain?

A

Soft paraffin

No preservative

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10
Q

What are the negatives of ointments?

A

Greasy

Restrict trans-epidermal water loss

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11
Q

What do pastes contain?

A

FInely powdered material (ZNO)

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12
Q

What are creams used for?

A

In drying, cooling and soothing bandaged

Often used on leg ulcers

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13
Q

What are the negatives of creams?

A

Stiff, greasy and difficult to apply

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14
Q

What are lotions?

A

Liquid formation

Suspension or solution of medication in water, alcohol or another liquid

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15
Q

Where are lotions used to treat?

A

The scalp or hair bearing areas

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16
Q

What are foams?

A

Hydrophillic liquid in continuous phase with foaming agent dispersed in gaseous phase

17
Q

What are the benefits of foams?

A

Increased penetration of active agents
Can spread easily over large area of skin
No greasy/oily film

18
Q

What are some types of topical therapies?

A
Emollients
Topical steroids
Anti-infective agents
Antipruritics
Keratolytics
Psoriasis therapies
Wet wrap therapy
19
Q

What do emollients do?

A

Enhance the rehydration of the epidermis

20
Q

What are emollients used for?

A

All dry/scaly conditions

21
Q

What is the dose of emollients?

A

300-500g weekly

22
Q

What do topical steroids do?

A

Vasoconstriction
Anti-inflammatory
Anti-proliferative

23
Q

What are some examples of topical steroids?

A

Hydrocortisone
Modrasone clobetasoone butyrate
Mometasone betamethasone valerate
Clobetasol proprionate

24
Q

What are topical steroids used for?

A

Eczema
Psoriasis
Lichen planus
Keloid scars

25
Q

What are the side effects of topical steroids?

A
Thinning of the skin
Purpura
Stretch marks
Steroid rosacea
Perioral dermatitis
May worsen infections
Systemic absorption causing adrenal suppression or cushings
Rebound flare
26
Q

What are antiseptics used for?

A

Recurrent infections
Antibiotic resistance
Wound irrigation

27
Q

What are examples of antiseptics?

A

Povidone iodine skin cleanser
Chlorhexidine
Triclosan
Hydrogen peroxide

28
Q

What are antivirals used for?

A

Herpes simplex
Eczema herpeticum
Herpes zoster

29
Q

What are antifungals used for?

A

Candida
Dermatophytes
Piityrasis versicolor

30
Q

What are examples of anti-pruritics?

A

Menthol
Capsaicin
Camphor
Crotamiton

31
Q

What are Keratolytics used for?

A
Softening kerating
Viral warts
Corns
Calluses
Hyperkeratotis eczema and psoriases
32
Q

What are some treatments for psoriasis?

A
Emollients
Coal tar
Vitamin D
Keratolytics
Dithranol
33
Q

What are treatments for scalp psoriasis?

A

Greasy ointments to soften scale
Tar shampoo
Steroids in alcohol based shampoo

34
Q

What is wet wrap therapy used for?

A

Very dry xerotic skin