Photodermatology Flashcards

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1
Q

What is photobiology?

A

The study of non-ionizing radiation on living systems

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2
Q

What are the two branches of photodermatology?

A

Diagnostic

Therapeutic

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3
Q

What can photodermatology be used to diagnose?

A

Photodermatoses

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4
Q

What waves are used in therapeutic photodermatology?

A

PUVA
-Shorter waves
UVB
-Longer waves

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5
Q

What is normal cutaneous photosensitivity?

A

Where the skin reacts normally to sun exposure, such as a burn or a tan

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6
Q

How is normal cutaenous photosensitivity classified?

A

Fitzpatrick classification SPT 1 to 4

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7
Q

What is abnormal cutaneous photosensitivity?

A

Where the skin reacts abnormally to sun exposure, such as urticaria or dermatitis

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8
Q

How long does sunburn take to develop after sun exposure?

A

3-4 hours

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9
Q

When does sunburn peak after sun exposure?

A

12-16 hours

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10
Q

What are the main groups of porphyrias?

A

Phototoxic skin porphyria
Blistering and skin fragility problems
Acute attach porphyrias
Severe congenital porphyrias

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11
Q

What do photoxic skin porphyrias present with and how is this relieved?

A

Pain, prickling and burning sensation

Relieved by cold water

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12
Q

How does Porphyria cutanea tarda (PCT) present?

A
Blisters
Skin fragility
Hyperpigmentation
Hypertrichosis
Solar urticaria
Morphoea
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13
Q

What are some possible underlying causes for PCT?

A

Alcohol
Viral hepatitis
Oestrogens
Haemochromotosis

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14
Q

What are the aims of PCT treatment?

A

Relieve skin disease
Treat underlying disease
Reduce risk of liver cirrhosis

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15
Q

What is more common PCT or EPP?

A

PCT

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16
Q

What does EPP stand for?

A

Erythropoietic protoporphyria

17
Q

What investigations can be done for suspected EPP?

A
Quantitative RBC porphyrins
Flurocytes
Transaminases
HB
Bilary tract USS
Phototesting
18
Q

What does the management of EPP entail?

A
Explain the diagnosis
6 monthly LFTs and RBC
Visible light photoprotection
Prophylactic TL-01 phototherapy
Anti-oxidants
19
Q

What is visible light photoprotection?

A

Wear dark clothing
Stay indoors
Topical sunscreen

20
Q

What can cause Acute intermittent porphyria?

A

Acute abdomen
Mononeuritis multiplex
Guillian-Barre syndrome
Psychoses