Theories of Aging Flashcards
Aging
Gradual and spontaneous changes that occur in maturation from infant to young adult - these changes create a normal physiologic decline seen in middle and late adulthood
Senescence
To grow old
The way scientists approach changes associated with aging
A degenerative process
Most health care dollars are spent on
managing diseases
5% healthcare dollars –> preventative care in 2015
Ageism
Can be seen as a process of systematic stereotyping of and discrimination against people because they are old
Old people are stereotypically chategorized as
Senile, rigid in thought and manner, old fashioned in morality and skills
Primary Aging
Aging that is independent of disease and environmental influences (intrinsic aging)
Determined by genetics
Secondary Aging
Aging superimposed upon genetic environment (extrinsic aging)
Changes due to environment and disease
May be modified
Aging (1/3..)
1/3 disease + 1/3 disuse + 1/3 normal aging
Aging - decreased
homeostatic reserve
less ability to restore baseline function
major loss leads to immobility
Aging - dec homeostatic reserve - consequences
inc dependence
inc risk of falls
inc types of aging
Disease vs. Normal aging (5) - Peola Timiras
- Aging is universal process shared by all living organisms
- Aging is intrinsic, dependent on genetic factors where disease is intrinsic or extrinsic
- Aging is always progressive where disease may progress or regress
- Aging is always deleterious whereas disease is occasionally deleterious
- Aging is irreversible where disease can be treated
Age related changes
Changes associated with aging through adulthood into age are gradual
Adults and aging rate
Factors impact aging
Adults age at different rates
Unique combination for each individual of biological, social, economic, psychological factors impacting aging
Factors affecting rate of aging - Biological changes
Changes in anatomy/physiology
Usually first to be noticed
Used to stereotype person as old
Theories of aging
No universally accepted theory
2 categories of aging theories
Programmed theories - aging as internal biological clock
Error theories - aging is result of internal and external assaults that damage cells or organs so they can no longer function properly
Programmed theories
Hayflick limit theory
Telomere theory
Endocrine/Hormonal Theory
Immunologic Theory
Hayflick Limit Theory
Aging is intrinsic - cells can only divide so many times and then shut off/die
Accumulation of improper functioning cells are responsible for aging
Dec DNA
Telomeric Theory
Cells keep track of their age through shortening of telomeres
Creates gap where end of chromosome can’t be copied
Telomere shortening alters expression of other genes which enables detrimental genes to become active
Telomeric theory - shorted telomere are found in
Atherosclerosis Heart disease Hepatitis Cirhosis Cancer - cancer cells have telomerase which can fill the gaps so they continue to develop and divide
Endocrine/Hormone Theory
Functional decrements in neurons and their associated hormones impact aging - effect growth, metabolism, temp, inflammation, and stress
Immunologic Theory
Decline in immune system
Inc vulnerability to disease, aging, death
Immune system is coded overtime to erode