The stuff professors have said is "important to know"

Question 1

Sunburns are caused by UV___

Answer 1

B

Question 2

What is the major UVB chromophore in the skin?

Answer 2

DNA

Question 3

Pattern seen with bed bug bites

Answer 3

linear group of 3 (breakfast, lunch, and dinner)

Question 4

How do we get Chagas disease?

Answer 4

Reduviid Bug (aka kissing bug) bites you then shits in there after feeding, their shit carries T. cruzi, the causative agent/microbe

Question 5

Daily shedding from scalp is ____ hairs

Answer 5

100

Question 6

What is telegen effluvium?

Answer 6

excess shedding of telogen hair due to pre-mature shunting of anagen to telogen phase = loss og 20-30% of total scalp hair but it will grow back

Question 7

circular shape of complete hair loss with a normal scalp is diagnostic of…

Answer 7

alopecia areata

Question 8

Proximal subungal pattern of onychomycosis is assc with

Answer 8

immunosuppression/HIV infection

onychomycosis = fungal infection of the nail, most commonly caused by trichophyton rubrum

Question 9

What nail disorder is assc with the elderly

Answer 9

onychogryphosis

= thick, haird, yellow-brown nail plate with asymmeteric growth (hallux is most frequently affected)

Question 10

What is the most frequent malignant tumor of the nail apparatus?

Answer 10

squamous cell carcinoma

**suggested to be caused by HPV

Question 11

In cutaneous SCC, risk of metastasis is related to:

Answer 11

size (>2cm = increased risk)
depth (deeper than 4mm)
anatomic site (worse = lips, ears)
host immune status

**When you can’t let SCC “SLIDE…

Question 12

Most important prognosis factors in melanoma?

Answer 12

Histological:

1. Breslow thickness
2. ulceration

Non-histo, but MOST important overall:
LYMPH NODE INVOLVEMENT

Question 13

Drug for unresectable or metastatic (stage 4) melanoma

Answer 13

vemurafenib

*modest survival benefit (in class he apologized for making us learn a drug name..)