The spleen continued Flashcards

1
Q

Surrounding the central arteriole is _____, made up of
________

A

Surrounding the central arteriole is PALS, made up of
T cells (T-cell zone).
Lymphocytes and antigen-loaded dendritic cells
come together here.

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2
Q

The follicles consist mainly of which cells in the spleen

A

he follicles consist mainly of B cells (B-cell zone)
 In secondary follicles, a GC is surrounded by a B-cell corona.

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3
Q

The follicles are surrounded by what?

A

The follicles are surrounded by a so-called MZ of
lymphocytes (DCs, macrophages, non-circulating
marginal B cells).

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4
Q

Both follicles and PALs are surrounded by

A

PFZ

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5
Q

In each area of white pulp, blood carrying both
lymphocytes and antigen flows from a_______ _______ into a _______. From this arteriole
smaller blood vessels fan out, eventually terminating
in a specialized zone in the human spleen called PFZ,
which surrounds each MZ. Cells and antigen then pass

A

trabecular artery into a central arteriole

into the white pulp through open blood-filled
spaces in PFZ.

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