chapter 1. Flashcards

1
Q

The state of protection from foreign pathogens and substances (antigens)

A

Immunity

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2
Q

Immunology

A

studies resistance to infection and mechanisms used by
organisms to defend themselves against microorganisms or foreign particles
(immune response)

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3
Q

Foundations of immunolgy are made up of 2 things

A

cell biology an molecular biology (cells and blood)

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4
Q

Explain the difference between extracellular and intracellular organisms

A
  • Extracellular pathogens reside
    outside of the cells of organisms
    they infect
  • Intracellular pathogens mainly
    reside within the organism’s cells
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5
Q

What do the terms “anatomic” and “chemical substances” refer to when explaining immune responses?

A

anatomic= skin and mucosal substances

chemical= secreted antimicrobial substances and pH

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6
Q

Anatomic and chemical substances are refered to as what line of defense?

A

First line of defense against pathogens

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7
Q

Provide examples to the term “anatomic”

A

skin, oral mucosa, respiratory, epithelium, intestine

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8
Q

Provide examples of complement/antimicrobial proteins

A

C3, defensins. regally

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9
Q

examples of innate immune cells

A

macrophages, granulocytes, NK cells, and epithelial cells.

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10
Q

What are some sensor cells?

A

macrophages, neutropils, dendritic cells.

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11
Q

Examples of inflammatory inducers

A

Bacterial lipoplysaccharides, ATP, urate crystals,

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12
Q

Examples of mediators

A

cytokines, cytotoxicity

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13
Q

target tissue cause the production of

A

antimicrobial proteins. induction of intracellular antiviral proteins. killing of infected cells.

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14
Q

Pathogens fall into four major catergories what are they?

A

Viruses (intracellular pathogens)
Intracellular bacteria, protozoa, parasaites

extracellular bacteria, parasites, fungi

parasitic worms (extracellular)

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