chapter 1. Flashcards
The state of protection from foreign pathogens and substances (antigens)
Immunity
Immunology
studies resistance to infection and mechanisms used by
organisms to defend themselves against microorganisms or foreign particles
(immune response)
Foundations of immunolgy are made up of 2 things
cell biology an molecular biology (cells and blood)
Explain the difference between extracellular and intracellular organisms
- Extracellular pathogens reside
outside of the cells of organisms
they infect - Intracellular pathogens mainly
reside within the organism’s cells
What do the terms “anatomic” and “chemical substances” refer to when explaining immune responses?
anatomic= skin and mucosal substances
chemical= secreted antimicrobial substances and pH
Anatomic and chemical substances are refered to as what line of defense?
First line of defense against pathogens
Provide examples to the term “anatomic”
skin, oral mucosa, respiratory, epithelium, intestine
Provide examples of complement/antimicrobial proteins
C3, defensins. regally
examples of innate immune cells
macrophages, granulocytes, NK cells, and epithelial cells.
What are some sensor cells?
macrophages, neutropils, dendritic cells.
Examples of inflammatory inducers
Bacterial lipoplysaccharides, ATP, urate crystals,
Examples of mediators
cytokines, cytotoxicity
target tissue cause the production of
antimicrobial proteins. induction of intracellular antiviral proteins. killing of infected cells.
Pathogens fall into four major catergories what are they?
Viruses (intracellular pathogens)
Intracellular bacteria, protozoa, parasaites
extracellular bacteria, parasites, fungi
parasitic worms (extracellular)