ch.1 part 2 Flashcards
In response to
pathogens, vertebrate
immune systems use
two interconnected
systems….What are they?
Innate and adaptive immunity
describe the innate immune responses (general) 4 key items
- Fast, but nonspecific
- Present from birth
- Uses germ-line–encoded
recognition molecules - Uses phagocytic cells (such as macrophages)
adaptive immune responses described (general) 4 key items
- Humoral and cell-mediated responses
- Using B and T lymphocytes respectively
- Slower to develop: 5–6 days or more
- Use randomly generated antigen receptors
*Highly specific to individual antigen molecules
(substances recognized as foreign) - Learned from contact with a pathogen
Describe the response time, specificity, response to repeat infection, and major components of innate immunity
Response time- minutes to hours
specificity- limited and fixed
response to repeat infection- same each time
Major components- barriers (skin)
phagocytes; pattern recognition molecules
What are some examples of extracellular pathogens?
Bacteria(some can be intracellular), parasites, parasitic worms
Describe the response time, specificity, response to repeat infection, and major components of adaptive immunity
Response time- days
specificity- highly diverse; adapts to improve during the course of immune response
response to repeat infection-more rapide and effective with each subsequent exposure
Major components-t and b lymphocytes
Give me an example of an intracellular pathogen?
Mainly viruses such as tuberculosis( these survive in macrophages) so they can change the mrna and rna, and some (few) bacteria
innate immunity=
inflammation
Which is stronger innate or adaptive immunity?
adaptive
Does inflammation change
No. it is always the same. That is why it is part of innate immunity. There is no memory attached to inflammation.
adaptive immunity can also be reffered to as
acquired immunity
What are effectors?
Any cells that are cleaning up pathogens (both b and t cells)
