The pituitary gland Flashcards
What is a hormone?
A messenger carried from the organ where they are produced to the organ whcih they affect by means of the bloodstream
What is the difference between a peptide and a steroid (synthesis)
Peptide is synthesised as prohormones which required further processing (in inactive form)
Steroid is synthesised from cholestrol
What is the difference between a peptide and a steroid (storage)
Peptide it is stored in vesicles (regulatory secretion)
Steroid it is released immediately
What is the difference between a peptide and a steroid (receptors)
Peptide binds to receptors on cell membrane and transduce signal using 2nd messenger systems
Steroid bind to intracellular receptors to change gene expression regularly
Diagram of the pituitary
What are hypothalamic parvocellular neurons
Regulate anterior pituitary functions
Short, terminate on median eminence
Release hypothalamic factors into capillary plexus in median eminence
Hypothalamic regulatory factors carried by portal circulation to anterior pituitary
Diagram of anterior pituitary
What are the steps of the hypothalamo-pituitary portal system
Axon terminals of hypothalamic neurosecretory cells release hormones
Travel through portal system through leaky blood vessels
Arrive in anterior pituitary hormones
Either release or inhibit from anterior pituitary
Hormones leave via blood
What are smatotrophns
Growth hormone (somatotrophin)
What are lactotophs
Prolactin
What are thyrotrophs
Thyroid stimulatin ghormone (TSH)/ thyrotrophin
What are gonadotrophs
Luteinising hormone (LH)
Follicle stimulating hormone (FSH)
What are corticotrophs
Adrenocorticotrophic hormone (ACTH or corticotrophin)
What hormone triggers the release of growth hormone
Growth hormone releasing hormone
(Inhibitory) somatostatin
What hormone triggers the inhibition of prolactin
Dopamine