the nervous system - physiology Flashcards
two types of cell in nervous tissue
-neurones
-neuroglia
neurones
-generate and transmit nerve impulses
-10^11 neurones (100billion)
-unable to replicate
neuroglia
-provide a supportive connective tissue
-10^12 (1trillion) glial cells
-able to replicate (i.e. can repair)
types of glial cells
the excitable neurones in the CNS are supported by non-excitable glial cells
-astrocytes: blood brain barrier (BBB)
-oligodendrocytes: myelin
-ependymal cells : CSF
-microglia: phagocytes
neurone structure
-cell body
-1 axon
-many dendrites
-axon hillock
neurones: cell body
-forms GREY matter of the nervous system
=periphery of brain
=centre of spinal cord
neurones: axons
-carry impulses away from cell body
-forms WHITE matter of nervous system
=centre of brain
=periphery of spinal cord
-tracts: bundles of axons in CNS
-nerves: bundles of axons in PNS
fast signal adaptations ?
-invertebrates: giant axons (1mm thick)
-vertebrates: myelin sheaths (electrical insulation)
myelin sheaths
-oligodendrocytes (CNS) or Schwann cells (PNS) produce fatty myelin to insulate electrical conduction
-fast conduction from node to node
neurones: dendrites
-numerous (1-10,000) short processes for incoming impulses
-often branching
-in sensory neurones form sensory receptors
-in motor neurones form part of synapses
function of neurones
-rapid transmission of nervous impulses
-transmission of impulses is both ELECTRICAL and CHEMICAL
rapid transmission of nervous impulses
-some neurones initiate nerve impulses
-other neurones relay impulses
transmission of impulses is both electrical and chemical
-electrical: (impulses called action potentials) down the nerve axon
-chemical: between adjacent neurones (synapse)
electrical conduction (action potential)
-transmission of impulses along an axon is ELECTRICAL
-an impulse is a wave of movement of ions across the nerve cell membrane
-requires co-ordinated opening/closing of ion channels to change the electrical potential across the membrane
=sodium (3Na+ out)
=potassium (2K+ in)
initiation of action potential
-initiated at the axon hillock
-threshold
=if exceeded an AP is triggered
=if not, no AP
=i.e. ‘all or nothing’ principle
-single AP is fast (<1ms)