The Muscular System. Flashcards

1
Q

What are the three types of muscle?

A

Skeletal, cardiac and smooth.

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2
Q

What are the 5 major functions of the muscular system?

A

Produce movement, maintain posture, support soft tissues, guard openings, and generate heat.

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3
Q

From largest to smallest, what are the different units of a muscle? (A box, inside of a box, inside of a box).

A

Belly/Body, Fascicle, Myofibril, Sarcomere, Myofilament.

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4
Q

The state of physiological inability to contract, even though the muscle still may be receiving stimuli.

A

Muscle Fatigue.

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5
Q

The extra amount of oxygen that the body must take in for restorative properties - the amount of oxygen required to convert accumulated lactic acid to glucose and to restore supplies of ATP and creatine phosphate.

A

Oxygen Debt.

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6
Q

Skeletal muscles are described as voluntary, but even relaxed muscles are almost always slightly contracted, a phenomenon called ____.

A

Muscle tone.

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7
Q

Muscle length changes (decreasing the angle at the joint), and moves the load. Once sufficient tension has developed to move the load, the tension remains relatively constant through the rest of the contractile period.

A

Isotonic contraction.

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8
Q

What are the two forms of isotonic contractions?

A

Concentric, and eccentric.

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9
Q

A contraction in which the muscle shortens, and does work - picking up a book, kicking a ball.

A

Concentric.

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10
Q

The muscle generates force as it lengthens, and are equally important for coordination and purposeful movements. Example: it occurs in the calf muscle as you walk up a steep hill.

A

Eccentric contraction.

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11
Q

Tension may build up to the muscle’s peak tension-producing capacity, but the muscle neither shortens nor lengthens. Example: the muscles around the knee in a squat.

A

Isometric contraction.

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12
Q

Compare concentric and eccentric contractions.

A

In a concentric contraction, the muscle shortens and does work, In an eccentric contraction, the muscle generates force and lengthens.

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13
Q

Compare isotonic and isometric contractions.

A

In an isotonic contraction, the muscle is either shortened or lengthened as it performs work. However, in an isometric contraction, the tension in the muscle may build up to a peak-tension, but the muscle does not shorten or lengthen.

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14
Q

Attachment of a muscle that remains relatively fixed during muscular contraction.

A

Origin.

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15
Q

Movable attachment of a muscle.

A

Insertion.

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16
Q

Cord of dense fibrous tissue attaching muscle to bone.

A

Tendon.

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17
Q

Fibrous or membranous sheet connecting a muscle and the part it moves.

A

Aponeurosis.

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18
Q

Bundle of nerve or muscle fibers bound together by connective tissues.

A

Fascicle.

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19
Q

A slender, threadlike structure or filament.

A

Fiber.

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20
Q

Sheath of fibrous connective tissue surrounding a muscle

A

Epimysium.

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21
Q

Connective tissue enveloping bundles of muscle fibers.

A

Perimysium.

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22
Q

The connective tissue surrounding each muscle cell.

A

Endomysium.

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23
Q

What causes muscle fatigue?

A

Muscle fatigue comes from strenuously exercising a muscle for a prolonged period of time. The muscle may lose it’s ability to contract due to interruption in the muscles blood supply, and therefore an interruption in the oxygen supply. However, it is most commonly associated with an accumulation of lactic acid in the muscle.

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24
Q

A wasting away or decrease in size of tissue, such as muscle fibers, usually from lack of use.

A

Atrophy.

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25
Q

What are the effects of lactic acid?

A

An increase in blood acidity, muscle fatigue.

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26
Q

How does aerobic exercise effect muscles?

A

The changes result in more efficient muscle metabolism, and in greater endurance, strength, and resistance to fatigue.

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27
Q

How does resistance exercise effect muscles?

A

Resistance exercises cause muscle hypertrophy and large gains in skeletal muscle strength.

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28
Q

Rodlike bundle of contractile filaments found in muscle fibers.

A

Myofibril.

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29
Q

Filament that constitutes myofibrils. Of two types - actin and myosin.

A

Myofilament.

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30
Q

where thick filaments are: the entire length of the thick filament.

A

A-Band.

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31
Q

The area of a sarcomere where there are only thin filaments -divided by Z-lines (which hold the actin in place)

A

I-Band.

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32
Q

Specialized endoplasmic reticulum of muscle cells. It’s interconnecting tubules surround each myofibril; most of these tubulues run longitudinally along the myofibril. Others form larger, perpendicular cross channels at the A-band/I-band junctions - these channels are called terminal cisternae and they always occur in pairs.

A

Sarcoplasmic reticulum.

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33
Q

At each A-band/I-band junction, the sarcolemma of the muscle cell penetrates into the cell interior, forming an elongated tube.

A

T-Tubule.

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34
Q

Describe the sliding filament mechanism of muscle contractions:

A

The sliding filament theory of contraction states that during contraction, the thin filaments slide past the thick ones so that the actin and myosin filaments overlap to a greater degree. In a relaxed muscle fiber, the thick and thin filaments only overlap at the ends of the A-band, but when muscle fibers are stimulated by the nervous system, the myosin heads latch onto the myosin binding sites on actin in the thin filaments, and the sliding begins.

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35
Q

How is smooth muscle different from skeletal muscle, in structure and action?

A

Smooth muscle is involuntary and non-striated, whereas skeletal muscle is both striated and voluntary.

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36
Q

What are the four sources of ATP for muscular contraction? Which are the most rapid?

A

Stored ATP, Creatine Phosphate, Anaerobic glycolysis, and Aerobic respiration - the most rapid is stored ATP.

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37
Q

What is the threshold stimulus/all or nothing concept of muscle stimulation?

A

The property in muscle and nerve fibres of either responding wholly to a stimulus or not at all. The strength of the stimulus must exceed a particular threshold or there will be no response, but when the response occurs it is total. The law applies to individual fibres and a graded response is obtained by a variation in the number of fibres activated.

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38
Q

What is a motor unit?

A

A motor neuron and all of the muscle fibers it supplies.

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39
Q

What is a muscle twitch?

A

The response of a motor unit to a single action potential of it’s motor neuron. The muscle fibers contract quickly and then relax.

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40
Q

Describe the process of creatine phosphate as it relates to ATP.

A

The CP stored in the muscles are tapped to regenerate ATP while the metabolic pathways are adjusting to the suddenly higher demands for ATP.

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41
Q

Describe the process of anaerobic glycolysis as it relates to ATP production.

A

As stored ATP and CP are used, more ATP is generated by catbolism of glucose obtained from the blood or by breakdown of glycogen stored in the muscle. During glycolysis, glucose is broken down into two pyruvic acid molecules, releasing enough energy to form small amounts of ATP. While pyruvic acid normally then enters the mitochondria and reacts with oxygen to produce more ATP, but when muscles contract vigorously, the muscles compress blood flow, and most of the pyruvic acid is then transformed into lactic acid.

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42
Q

Describe the process of aerobic respiration as it relates to the production of ATP:

A

Aerobic respiration occurs in the mitochondria, requires oxygen, and involves a sequence of chemical reactions in whch the bonds of fuel molecules are broken and the energy released is used to make ATP. During this process, glucose is broken down entirely, yielding water, carbon dioxide and large amounts of ATP as the final products.

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43
Q

What is the role of troponin and tropomyosin?

A
  1. cross bridge-binding of actin and myosin
  2. Roles are to regulate formation of cross bridges this regulation is done using Ca, in absence of Ca, tropomyosin blocks the actin myosin binding sites
  3. When Ca is present it binds to TnC, causing a conformational change to the troponin complex that forces torpomyosin to move away from the actin myosin binding iste

thus allowing actin to bind to myosin and form the cross bridge.

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44
Q

What are spatial or temporal wave summations?

A

increasing the number of stimuli delivered to a given motor unit per time.

Results in increased Ca concentration which then causes more tension/shortening.

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45
Q

Name the four rotator cuff muscles:

A

Supraspinatus muscle
Infraspinatus muscle
Teres minor muscle
Subscapularis muscle

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46
Q

What muscles are involved in smiling?

A

Zygomaticus, orbicularis oris, Levator labii superioris, risorius.

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47
Q

What are the muscles involved in frowning?

A

Mentalis, depressor anguli oris, depressor labii inferioris.

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48
Q

Condition that occurs when the load is close to the fulcrum, and the effort is applied far from the fulcrum; allows a small effort exerted over a relatively large distance to move a large load over a small distance.

A

Mechanical advantage.

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49
Q

Condition that occurs when the load is far from the fulcrum and the effort is applied near the fulcrum; the effort applied must be greater than the load to be moved.

A

Mechanical disadvantage.

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50
Q

What mechanical support system provides power?

A

Mechanical advantage.

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51
Q

What mechanical support system provides speed?

A

Mechanical disadvantage.

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52
Q

Partnerships between the muscular and skeletal systems.

A

Lever systems.

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53
Q

A rigid bar that moves on a fixed point.

A

Lever.

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54
Q

In the body, the ___ are the fulcrum.

A

Joints.

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55
Q

In the body, the ___ act as the levers.

A

Bones.

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56
Q

In the body, the ___ are the applied force.

A

Muscles.

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57
Q

The weight to be moved.

A

Load.

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58
Q

In the body, the ____ is the weight of muscle; weight of body or object in hand.

A

Load.

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59
Q

The fixed point on which a lever moves.

A

Fulcrum.

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60
Q

The load is the ____ itself, along with overlying tissues and anything else that is trying to be moved.

A

Bone.

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61
Q

These levers are useful because they provide rapid contractions with a wide range of motion.

A

Mechanical disadvantage.

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62
Q

Effort farther than than load from fulcrum =

A

Mechanical advantage.

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63
Q

Effort nearer than load to fulcrum=

A

Mechanical disadvantage.

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64
Q

In _____, the effort is applied at one end of the lever and the load is at the other, with the fulcrum somewhere between.

A

First-class lever.

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65
Q

What is an example of a first-class lever in the body?

A

Lifting your head away from your chest - extension of the neck.

66
Q

In a _____, the effort is applied at one end of the lever, and the fulcrum is located other, with the load between them.

A

Second-class lever.

67
Q

What is an example of a second-class lever in the body?

A

The act of standing on your toes - plantar flexion.

68
Q

In ____, the effort is applied between he load and the fulcrum.

A

Third-class levers.

69
Q

What is an example of a third-class lever in the body?

A

The bicep muscles of the arms.

70
Q

The fascicular pattern is ____ when the fascicles are arranged in concentric rings.

A

Circular.

71
Q

Give an example of a circular fascicle arrangement.

A

The orbicularis muscles surrounding the eyes and mouth.

72
Q

A general term for circular fascicular arrangement is:

A

sphincters.

73
Q

A ____ muscle has a broad origin, and its fascicles converge toward a single tendon of insertion.

A

Convergent.

74
Q

What is an example of a convergent fascicle arrangement?

A

The pectoralis major.

75
Q

In a ____ arrangement, the long axes of the fascicles run parallel to the long axis of the muscle.

A

Parallel.

76
Q

Such muscles are either strap-like, or spindle shaped with an expanded belly.

A

Parallel.

77
Q

What is an example of a parallel arrangement of fascicles?

A

The biceps brachii.

78
Q

In a ____ pattern, the fascicles are short and they attach obliquely to a central tendon that runs the length of the muscle.

A

Pennate.

79
Q

If the fascicles insert into only one side of the tendon, the muscle is ____.

A

Unipennate.

80
Q

What is an example of a unipennate fascicle arrangement?

A

The extensor digitorum.

81
Q

If the fascicles insert into the tendon from opposite sides, so that a muscles “grain” resembles a feather, the arrangement is ____.

A

Bipennate.

82
Q

What is an example of a bipennate fascicle arrangement?

A

The rectus femoris of the thigh.

83
Q

A _____ arrangement looks like many feathers situated side by side, with all their quills inserted into one large tendon.

A

Mutipennate.

84
Q

What is an example of a multipennate fascicle arrangement?

A

The deltoid muscle.

85
Q

What are the four criteria used in naming muscles?

A
  • Location; bone or body region associated w the muscles
  • Shape; deltoid muscle deltoid=triangle
  • Relative size; maximus largest minimus smallest, longs long
  • Direction of fibers or fascicles; rectus fibers run straight, Transversus and oblique fibers run at angles.
86
Q

What are the different quadricep muscles?

A

Rectus femoris, vastus lateralis, vastus medialis, vastus intermedius.

87
Q

Muscle that bears the major responsibility for effecting a particular movement; an agonist.

A

Prime mover.

88
Q

Muscle that aids the action of a prime mover by effecting the same movement or by stabilizing joints across which the prime mover acts to prevent undesirable movements.

A

Synergists.

89
Q

Muscle that reverses, or apposes, the action of another muscle.

A

Antagonist.

90
Q

Muscle that immobilizes one or more bones, allowing other muscles to act from a stable base.

A

Fixator.

91
Q

a measure of how many motor neurons are activated in a particular muscle, and therefore is a measure of how many muscle fibers of that muscle are activated. The higher the recruitment the stronger the muscle contraction will be.

A

Motor unit recruitment.

92
Q

5 Steps to Stimulate a Muscle Fiber:

A

(1) Action Potential (AP) arrives in synaptic terminal
(2) Acetlycholine (ACh) is released by Neuron
(3) Ach binds to motor end plate….allows Na+ ions to enter fiber
(4) Na+ rush creates an Action Potential in the sarcolemma
- AP is a de-polarizing wave that moves along the entire membrane
- This wave passes through the sarcolemma, into the Transverse Tubules
- AP on TT causes the SR to depolarize
(5) Depolarized SR membranes release Ca and starts contraction process.
(6) Acetylcholine is destroyed by the enzyme acetylcholinesterase. (AchE)

93
Q

Describe the process of a smooth muscle contraction:

A

Smooth muscle fibers may be electrically coupled by gap-junctions, and the pace of contraction may be set by pace maker cells. Smooth muscle contraction is energized by ATP, and is activated by a calcium pulse. However, calcium binds to calmodulin rather than to troponin (which is not present in smooth muscle fibers) and the myosin heads must be phosphorylated to become active in contraction.

94
Q

What is a gap junction?

A

A passageway between two adjacent cells.

95
Q

What is muscle hypertrophy?

A

Increase in size of a tissue or organ.

96
Q

What is phosphorylation?

A

A chemical reaction in which a phosphate molecule is added to a molecule.

97
Q

What role does calmodulin play in smooth muscle contraction?

A

calcium binds to calmodulin rather than to troponin (which is not present in smooth muscle fibers) and the myosin heads must be phosphorylated to become active in contraction.

98
Q

Describe the gross contraction of a skeletal muscle:

A

A motor units response to a single brief threshold stimulus is a twitch - graded responses of muscles to rapid stimulation are wave summation and tetanus, and isotonic contraction occurs when the muscle shortens or lengthens.

99
Q

A state of sustained contraction of a muscle that is a normal aspect of skeletal muscle functioning.

A

Tetanus.

100
Q

Describe the microscopic anatomy of a skeletal muscle:

A
  • Skeletal muscle fibers are long, striated and multi-nucleate.
  • Myofibrils are contractile elements that occupy most of the cell volume, and their banded appearance results from the regular alternation of dark (A-Band) and light (I-band).
  • The sarcoplasmic reticulum is a system of membranous tubules surrounding each myofibril, and it’s function is to secrete and then sequester calcium ions.
  • T-Tubules are invaginations of the sarcolemma that run between the terminal cisternate of the SR. They allow the electrical stimulus to be delivered quickly to deep cell regions.
101
Q

What is a cross-bridge?

A

the globular head of a myosin molecule that projects from a myosin filament in muscle and in the sliding filament hypothesis of muscle contraction is held to attach temporarily to an adjacent actin filament and draw it into the A band of a sarcomere between the myosin filaments

102
Q

What are the three types of muscle fibers?

A
  • Fast glycolytic. (fatigable fibers)
  • Slow oxidative. (fatigue-resistant)
  • Intermediate fast oxidative. (fatigue resistent)
103
Q

What are the two types of fatigue-resistant muscle fibers?

A

Slow oxidative, and intermediate fast oxidative.

104
Q

______ has independent, well-innervated fibers that lack gap junctions, and pacemaker cells. Stimulation is via autonomic nerves.

A

Multi-unit smooth muscles.

105
Q

Type of smooth muscle; its cells contract as a unit and rhythmically, are electrically coupled by gap junctions, and often exhibit spontaneous action potentials.

A

Visceral muscle.

106
Q

Contrast visceral and multi-unit smooth muscle:

A

Whereas, visceral smooth muscle is large & relatively powerful, multiunit smooth muscle is small & delicate. Instead of being formed into large sheets that function as a single large unit, multiunit smooth muscle is made up of individual smooth muscle cells or small groups of cells. Also like visceral smooth muscle, contractions of multiunit smooth muscle are not automatic. They require specific impulses from autonomic nerves to contract

107
Q

Where is visceral muscle found?

A

The walls of many smooth internal organs - intestines, bladder, uterus.

108
Q

Where is multi-unity smooth muscle found?

A

It is found where small, delicate contractions are needed, such as in the iris & ciliary body of the eye, the walls of small blood vessels, & around small air passageways in the lungs.

109
Q

What is peristalsis?

A

Progressive, wavelike contractions that move substances through hollow body organs.
- Example: Food through the intestines.

110
Q

What muscles are used to breathe in?

A

Diaphragm and external intercostals.

111
Q

What muscles are used to breathe out normally?

A

In normal exhalation, no muscles are used to exhale - the diaphragm simply releases pressure.

112
Q

What muscles are used to breathe our forcibly?

A

Internal intercostals and abs.

113
Q

Compare origin and insertion:

A

The origin is the fixed attachment, while the insertion moves with contraction.

114
Q

Give an example of a muscle named by relative size:

A

Gluteus maximus, pectoralis major.

115
Q

A muscle named by body region:

A

Frontalis.

116
Q

A muscle named by the number of origins:

A

Biceps brachii.

117
Q

A muscle named by the direction of fibers:

A

Rectus abdominis.

118
Q

A muscle named by shape:

A

Deltoid.

119
Q

A muscle named by action:

A

Extensor digitorum.

120
Q

What muscles are, or could be, involved with a pulled groin?

A

The abductor muscles.

121
Q

What muscles are, or could be, involved with a shin splint?

A

Flexor digitorum longus, gastrocnemius, soleus.

122
Q

What muscles are, or could be, involved with a pulled hamstring?

A

Biceps Femoris muscle, the Semitendinosus muscle, and the Semimembranosus muscle.

123
Q

What muscles are, or could be, involved with a wry neck?

A

sternocleidomastoid muscle or the trapezius

124
Q

What muscles are, or could be, involved with lower back pain?

A
125
Q

What muscles are involved in chewing(mastication)?

A

Temporalis, buccinator, masseter.

126
Q

What are the hamstring muscles?

A

Biceps Femoris muscle, the Semitendinosus muscle, and the Semimembranosus muscle.

127
Q

What muscles make up the erector spinae?

A

Spinalis, Longissimus, Iliocostalis.

128
Q

What is the difference between muscle cramps and muscle fatigue?

A

Muscle fatigue is the inability for a muscle to contract, meanwhile a muscle cramp is a sudden and involuntary contraction of one or more of your muscles

129
Q

What type of muscle contraction allows the generation of the most force?

A

Isotonic.

130
Q

How does muscle tone affect overall body health and fitness?

A

The primary purpose of muscle tone (as per its real definition) is to keep your muscles primed and ready for action. The always activated state of partial contraction maintains balance and posture, and it also functions as a safety mechanism that allows for a quick, unconscious muscle reflex reaction to any sudden muscle fiber stretch. Muscle tone also generates heat and keeps your muscles healthy. If the nerve to a particular muscle is damaged, it may no longer be able to stimulate the muscle contractions necessary to maintain muscle tone and the muscle will become flaccid and eventually it will deteriorate.

131
Q

What are the origins and insertions of the zygomaticus major?

A

It originates on the zygomatic bone and inserts through the skin and muscle at the corner of the mouth.

132
Q

What are the origins and insertions of the masseter?

A

It originates from the zyomatic arch and maxillary bone, and inserts and the angle and ramus of the mandible.

133
Q

What are the origins and insertions of the temporalis?

A

It originates from the temporal fossa of the temporal bone, and inserts at the coronoid process of the mandible.

134
Q

What are the origins and insertions of the sternocleidomastoid?

A

Origin: Manubrium of sternum and clavicle
Insertion: Mastoid process of temporal bone and the occipital bone

135
Q

Origins and insertion of the deltoid:

A

Origin: Acromion and spine of scapula, lateral third of clavicle
Insertion: Deltoid tuberosity of humerus8

136
Q

Origins and insertions of the pectoralis major:

A

Origin: Rib 1 - 8
Insertion: Vertebral border of scapula

137
Q

What are the origins and insertions for the external intercostals:

A

Origin: Inferior border of each rib
Insertion: Superior border of adjacent rib below

138
Q

Origin and insertion for the rectus abdominis:

A

Origin: Pubic crest and symphysis
Insertion: Xiphoid process and costal cartilages of ribs 5-7

139
Q

Origin and insertion for the trapezius:

A

Origin: Occipital bone, ligamentum nuchae; spines of C7 and all thoracic vertebrae
Insertion: Acromion and spine of scapula; lateral third of clavicle

140
Q

Origin and insertion of the subscapularis:

A

Origin: Subscapular fossa of anterior scapula
Insertion: Lesser tubercle of humerus

141
Q

Origin and insertion of the supraspinatus:

A

Origin: Supraspinous fossa of the scapula
Insertion: Greater tubercule of humerus

142
Q

Origin and insertion of the biceps brachii:

A

Origin: Short head at coracoid process of scapula, long head at supraglenoid tubercle of the scapula through the intertubercular groove
Insertion: Radial tuberosity of the radius

143
Q

Origin and insertion of the brachialis:

A

Origin: Distal portion of the humerus
Insertion: Styloid process of the radius

144
Q

Origin and insertion of the brachioradialis:

A

Origin: Distal end of humerus
Insertion: Styloid process of radius

145
Q

Origin and insertion of the flexor carpi radialis:

A

Origin: Medial epicondyle of humerus
Insertion: Base of 2nd and 3rd metacarpals

146
Q

Origin and insertion of the externsor carpi ulnaris:

A

Origin: Lateral epicondyle of humerus
Insertion: Base of 3rd metacarpal

147
Q

Origin and insertion of the gluteus maximus:

A

Origin: Posterior side of ilium, sacrum and coccyx
Insertion: Gluteal tuberosity of femur, iliotibial tract

148
Q

Origin and insertion of the tensor fasciae latae:

A

Origin: Anterior side of iliac crest and anterior superior iliac spine
Insertion: Iliotibial tract

149
Q

Origin and insertion of the sartorius:

A

Origin: Anterior superior iliac spine
Insertion: Medial side of proximal tibia by aponeurosis

150
Q

Origin and insertion of the adductor magnus:

A

Origin: Ischial and pubic rami, ischial tuberosity
Insertion: Linea aspera and adductor tubercle of femur

151
Q

Origin and insertion of the rectus femoris:

A

Origin: Anterior inferior iliac spine, superior margin of acetabulum
Insertion: Tibial tuberosity and patella

152
Q

Origin and insertion of the tibialis posterior:

A

Origin: Superior part of tibia and fibula
Insertion: Tarsals, metatarsals 2-4

153
Q

Origin and insertion of the fibularis longus:

A

Origin: Head and shaft of fibula
Insertion: By long tendon to 1st metatarsal and medial cuneiform

154
Q

Origin and insertion of the tibialis anterior:

A

Origin: Lateral condyle and superior shaft of tibia
Insertion: By tendon onto cuneiform and 1st metatarsal

155
Q

What are the primary cause in muscle cramps and how are they treated?

A

Muscle cramps are said to be caused by excessively excited nerves, dehydration, low levels of calcium, magnesium or potassium. Cramps are typically treated with relaxation of the muscle, stretching, and hydration.

156
Q

What is muscular dystrophy and what causes it?

A

Muscular dystrophy is a group of genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. It is caused by missing or abnormal dystrophin, a protein that holds skeletal muscle cells together.

157
Q

What is excitation-contraction coupling?

A

the link between excitation of muscle membrane and initiation of force generation at cross-bridges, producing muscle contraction

158
Q

What muscles are responsible for flexion of the elbow?

A

Biceps brachii, brachialis, brachioradialis, pronator teres.

159
Q

What mucles are responsible for extension of the elbow?

A

Triceps brachii, anconeus.

160
Q

What muscles are responsible for flexion of the knee?

A

sartorius, gracilis, biceps femoris, semitendinosus, semimembranosus, gastrocnemius, plantaris, popliteus.

161
Q

What muscles are responsible for extension of the knee?

A

Rectus femoris, vastus muscles.