The Mechanism Of Enzyme Action Flashcards
Describe the lock and key hypothesis
The theory that an enzymes active site is specific to only one kind of substrate. The basic explanation of ESC.
What is an EP complex?
An enzyme product complex is the stage when the product has been formed just before the enzyme releases it.
What is an ES complex?
When temporary hydrogen bond hold the enzyme and substrate together.
What is the induced fit hypothesis?
The idea that the active site changes slightly once the substrate has entered so that it gives a more precise conformation that exactly fits the substrate. Allowing the substrate to bind more effectively.
What non-covalent forces assist the bonding of the substrate and enzyme?
Hydrogen binds, ionic attractions, van dear Waals forces as hydrophobic interactions.
Why do enzymes lower the activation energy of a reaction?
They require less heat energy than if there were no enzymes. Because they have an active site specific to substrates they bring the substrate molecules close enough to each other to react.
