The LIst Exam 4 Flashcards
Adenovirus
Linear, double stranded DNA
Non-enveloped
Usually respiratory infection… colds (can cause rash, conjunctivitis, gastroenteris)
Birds, humans, mammals
Human papillomavirus
HPV
DNA
Infects skin and mucous membranes
30% of people have it… most common viral STD
Smallpox Virus
Variola virus Double stranded DNA Enveloped and uneveloped Skin rash and blisters of skin, mouth, throat. Eradicated through vaccines Airborne transmission (droplets)
Vaccinia virus (cowpox)
Enveloped
Linear double stranded DNA
Cowpox
Used to eliminate smallpox
Herpes simplex virus
HSV1/2 or HHV1/2
Double stranded linear DNA Enveloped Oral herpes: sores in mouth 90% of people in US have contact by age 50 can be dormant… lessions last 2-3 weeks no cure
Cytomegalovirus (CMV)
DNA viruses
Can cause lytic (latent) infections
Genus of Herpesvirus
Species that infects humans is human CMV
Hepatitis B virus
Partially double stranded DNA and circular
Very small genome
Spread through blood and sexual contact
Abdominal pain, dark urine, yellowing of skin, nausea, loss of appetite, joint pain
Rhinovirus
Single stranded positive RNA Non-enveloped Aerosolized or direct contact Cold infections Late summer and late spring
Norovirus
ssRNA, (-) strand non-enveloped Person to person, foodborne, waterborne Extremely infectious Vomiting and diarrhea, nausea, cramps, chills, headache, fever half the time
Measles Virus
ssRNA (-) enveloped Morbillivirus Just humans, no animals Respiratory system: fever, coughm runny nose, rash Very contagious: coughing and sneezing
Mumps Virus
Rubulavirus ssRNA (-) enveloped Childhood disease: swelling of parotid and salivary glands High morbidity Deafness Vaccine-preventable
Dengue Fever
ssRNA (+) enveloped Mosquito borne 4 serotypes, all cause disease fever, headache, muscle and joint pain, skin rash like measles
West Nile Virus
ssRNA (+) enveloped same family as dengue and yellow fever Mosquito borne Fever, headache, rash, swollen lymph glands, stiff neck, paralysis
Yellow Fever Virus
ssRNA (+) Decreased number of neutrophils Blood in urine and feces Liver dysfunction Jaundice Starts like minor flu
Ebola Virus
ssRNA (-)
enveloped
Hemorrhagic fever
High fatality
Hantavirus
ssRNA (-) enveloped Haemorhagic feverl with renal syndrome Rodents Aerosolization and rodent bites Pneumonitis, congestion,
Rabies Virus
ssRNA (-) Enveloped Salvia of animals Travesl acros PNS quickly to CNS\ Spread to organs… projectile salivation Death after 2 years to 5 days
Influenza Virus
Usually ssRNA (-), sometimes double Spread through air from cough/sneeze
Merkel cell polyomavirus
dsDNA
non-enveloped
Human tumor viruses: cause 80% of Merkel cell carcinoma
Limitied sun exposure can prevent virus
Human immunodeficiency
virus (HIV)
ssRNA (+)
Causes AIDS
Rotavirus
dsRNA sometimes enveloped Resistant to hand washing Children Diarrhea Lots of yearly deaths
Hepatitis C virus
ssRNA (+) enveloped Can occur with Hep B Many also have a chronic infection Attacks liver Usually asymptomatic… can have fever, poor appetite, tired feeling
Epstein Barr virus (EBV or
HHV4)
dsDNA
enveloped
Only humans
Infectious mononucleosis: fever, sore throat, tonsillitis,
Cause disease by lysis of host cell or latency cycle
Kaposi’s sarcomaassociated
herpesvirus
(KSHV or HHV8)
dsDNA
Herpesvirus family
Causes cancer (Kaposis sarcoma), esp in AIDS patients
Castlesman’s disease
Cancer virus
Primary effusion lymphoma
Infection though to be lifelong, but can be kept in check if healthy person
Most don’t show symptoms unless immunocompromised
Varicella zoster virus (VZV
or HHV3)
dsDNA
enveloped
Chicken pox!
Also shingles
Severe acute respiratory
syndrome (SARS) virus
ssRNA (+) enveloped Muscle pain, headache, fever then Coughm dyspnea, pneumonia Decreased lymphocytes in blood 9% die
Chikungunya virus
ssRNA (+) enveloped Sudden fever for a week to 10 days Joint pain and stiffness (weeks to years) Rash, muscle pain, inflammation of eyes Can be chronic
Middle East Respiratory
Syndrome (MERS) virus
ssRNA (+)
From bats, camels: can be transmitted human to human?
Fever, cough, shortness of breath
Enterovirus D68
ssRNA (+)
non-enveloped
POLIO: fever, sore throat, headache, vomiting, stiffness of back/neck/limbs
No animals, just human
Enters through mouth, multiplies in intestine
Summer time in temperate
Children under age 5