The Integumentary System CH 7 Flashcards
Skin, Integument
is considered an organ system because of its extent and complexity.
Skin has two distinct regions
The superficial epidermis composed of epithelium and an underlying connective tissue, the dermis.
deep to the dermis
is the hypodermis or superficial fascia which is not considered part of the skin. it consists primarily of adipose tissue.
Stratum Corneum
(Horny layer) Most superficial layer, 20-30 layers of dead cells, essentially flat membranous sacs filled with keratin. constantly rubbing off and being replaced by division of the deeper cells. Glycolipids in extracellular space.
Stratum Granulosum
One to five layers of flattened cells, organelles deterioration, cytoplasm full of lamellar granules (release lipids) and keratohyaline granules.
Stratum spinosum
Several layers of keratinocytes joined by desmosomes. Cells contain thick web like bundles of intermediate filaments made of pre-keratin protein. The stratum spinosum cells appear spiky (hence their name) because as the skin tissue is prepared for histological examination, they shrink but their desmosomes hold tight. Immediately superficial to the basal layer.
Stratum basale
Deepest epidermal layer, one row of actively mitotic stem cells, some newly formed cells become part of the more superficial layers. Immediately adjacent to the dermis.
Stratum lucidum
(Clear layer) A very thin translucent band of flattened dead keratinocytes with indistinct boundaries. it is not present in regions of thin skin…. present in thick skin
Keratinocytes
(literally, keratin cells) The most abundant epidermal cells, their main function is to produce keratin fibrils.
Keratin
is a fibrous protein that gives the epidermis its durability and protective capabilities. Keratinocytes are tightly connected to each other by desmosomes.
Melanocytes
Spidery black cells that produce the brown-to-black pigment called melanin. the melanin provides a protective pigment umbrella over the nuclei of the cells in the deeper epidermal layers this shielding their genetic material (DNA) from the damaging effects of ultraviolet radiation. A concentration of melanin in one spot is called a freckle.
Dendritic cells
Also called Langerhans cells, these cells paly a role in immunity.
Tactile (Merkel) cells
Occasional spiky hemispheres that, in combination with sensory nerve endings, form sensitive touch receptors called tactile or Merkel discs located at the epidermal-dermal junction.
Dermis
The dense irregular connective tissue making up the dermis consists of two principal regions – the papillary and reticular areas.
Papillary layer
The more superficial dermal region composed of areolar connective tissue. It is very uneven and has fingerlike projections from its superior surface, the dermal papillae, which attach it to the epidermis above. these projections lie on top of the larger dermal ridges. In the palms of the hands and soles of the feet, they produce the fingerprints, unique patterns of epidermal ridges.
Reticular layer
The deepest skin layer. It is composed of dense irregular connective tissue and contains many arteries and veins, sweat and sebaceous glands, and pressure receptors (lamellar corpuscles).