The Integument (skin) Organ System Flashcards
What is the largest organ in the body?
the skin
What does the skin consist of?
Epidermis
Dermis: fibrous connective tissue
Hypodermis- NOT considered part of the integument. It’s just loose adipose CT lying just beneath the integument
What are some functions of the Integument?
Support Protect Body temp control excrete Vit D
What makes Thick skin different from thin?
Thick does not have hair or sebaceous glands
-covered by many layers of keratinized dead cells
What is the epidermis? (cell type)
keratinized, stratified squamos epithelium
What are the 4 main cell types in the epidermis?
Keratinocytes- most abundant
Melanocytes
Merkel cells- light touch
Langerhans cells- immune cells of the skin
Do free nerve endings that terminate near the upper layer of epidermis have CT or schwann cells?
No
What are the layers of the epidermis?
Stratum basale- deepest
Stratum spinosum- has lots of desmosomes so it looks spiny
Stratum lucidum (clear layer)- occurs only in thick skin, dead flat keratinocytes
Stratum Corneum- outermost layer, dead keratinocytes, protects skin
What is Callus (hyperkeratosis)?
a thickening of the skin in areas of constant friction of pressure due to accelerated keratinization that exceeds the rate of loss
-if friction is too extreme, it results in water blisters
Why do blisters of the epidermis occur?
because of a disruption of Desmosomes and hemidesmosomes
What usually causes blistering diseases?
autoimmune diseases
-can be treated with corticosteroids and immunosuppressive drugs
What makes up the leather obtained from an animal?
the dermis of their skin
What is the Dermis?
a strong, flexible CT made of dense, irregular fibrous CT
What is the primary cell type of the dermis?
fibroblasts
What fiber types are made in the dermis?
collagen, elastin, and reticular fibers