The Immune System Flashcards
The immune system helps _______ the body from ______; collects ______ lost from blood ______ and return it to the _____________ system
protect
disease
fluid
vessels
circulatory
timeline: 0 to 12 hours
consists of 1st and 2nd line of defence
innate immunity
(non specific defence mechanisms)
timeline: 1 to 7 days
consists of the 3rd line of defence
adaptive immunity
(specific defence mechanisms)
1st line of defence:
• skin
• mucous membranes
• secretion of skin
•secretion of mucous membranes
2nd line of defence:
• macrophages
• other phagocytes (i.e. neutrophils, NK cells)
• antimicrobial proteins
• inflammatory response (e.g. redness, fever)
3rd line of defence:
• lymphocytes (B & T cells)
• antigen-specific
• antibodies
• memory
includes the skin; mucous membranes; hair within the nose; cilia in the upper respiratory tract; urine; perspiration; saliva; stomach gastric juice; and sebum
1st line of defence
includes an inflammatory response and white blood cells (phagocytes) that ingest pathogens
2nd line of defence
the blood contains these cells to fight infection at both innate and adaptive immune levels
white blood cells
alternative name for white blood cells
leukocytes
where are white blood cells produced?
produced in the bone marrow
where do white blood cells come from?
come from stem cells
a common type of white blood cell of the innate immune system
phagocytes
phagocytes:
_____ and digest foreign particles such as _______ and dead or ________ cells in a process called ____________
engulf
bacteria
dying
phagocytosis
the process in which phagocytes engulf and digest foreign particles such as bacteria and dead or dying cells
phagocytosis
a common type of white blood cell of the adaptive immune system
lymphocytes
what are the two types of lymphocytes?
B cells
T cells
make antibodies
B cells
Y-shaped proteins that respond to a specific antigen on a virus, bacterium etc. and lock on to it
antibodies
B cells:
• make ________
• are specific on the ______
• attach on the ______ and create _______. this lessens movement of the ______ thus making them easier to be “_____ and _________” by ___________.
antibodies
invader
antigens
clumping
invaders
hunted
destroyed
macrophages
where are T cells produced
produced in bone
where do T cells mature
thymus gland
produce chemicals which signals B cells to make antibodies
helper T cells
actively attack invaders by puncturing their cell membrane and destroying them
killer T cells