The forebrain and cerebral cortex Flashcards

1
Q

Site the main component of the forebrain and localise them on the draw

A
N accumbens
Amygdala
Bed Ni of the stria terminalis
Caudate N
Caudate-Putamen
Habenula
Hippocampus
Hypothalamus
Globus Pallidus (GB)
Lateral GB
Medial GB
Putamen
Septum
Subthalamic N
Thalamus
Ventral Pallidum
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2
Q

Which are the different cortical type ?

A

Néocortex, Allo cortex and Mesocortex

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3
Q

What do we know about the allocortex?

A

Paleocortex (olfactory piriform cortex) - 4 to 6 layers

Achricortex - 3 layer - hippocampal formation.

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4
Q

What do we know about the mesocortex?

A

Transition cortex between the allocortex and the neocortex. It concern the enthorinal, perirhinal, cingulate, insula orbitofrontal, subcallosal retrospinal cortexes.

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5
Q

Site the layer forming the cytoarchitecture of the cortex.

A
I - Molecular layer
II - External granular layer
III - External pyramidal layer
IV - internal granular layer
V - internal pyramidal layer
VI - Multiform layer
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6
Q

Which differences can we observe at the cytoarchitectural level between the sensory, motor and other cortical region ?

A

Motor : Heteroypical cortex, agranular (very small IV layer, layers III and V developped)
Sensory : Heterotypical ( L III and V reduced, IV developped)

other : homotypical, 6 developped layers

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7
Q

Cite the different type of cells you can find in the homotypical cortex.

A
Pyramid neurones
Modified pyramid
Horizontal cells
Chandelier cells
aspiny stellate 
Spiny stellate
Basket
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8
Q

Describe the pyramid cells.

A

Layer V and III
Dendrites project horizontaly in every layers.
Glutamatergic neurones (excitatory)
axon project corticofugaly or to the corrtex
70-80% of the cortex volume

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9
Q

Describe modified pyramid cells

A

C body in layer VI
Dendrires un layer IV and VI
project to the thalamus & to the cortex
glutalatergic

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10
Q

Describe Horizontal cells

A

Dendrites and cell body in layer 1

Periphery of the cortex

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11
Q

Describe chandelier cells

A

Layer III
GABAergic interneurones
It is believed that they provide inhibitory input to the pyramidal neurons, but there is data showing that in some circumstances the GABA from chandelier neurons could be excitatory.
Axons L II and III

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12
Q

Where are SPiny stellate cells located ?

A

Layer IV

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13
Q

Where are basket cells located ?

A

W/ pyramidal cells, L V and IV

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14
Q

What are the differences between SPiny stellate and A stellate cells ?

A

SPiny stellate: excitatory interneurons
C body L IV
dendrite IV
axon II

aspiny interneurones : C body, dendrites and axon L IV, GABAergic(inibitory) interneurons
Large arborisation

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