Cerebellum

Question 1

How cerebral cortex is linked to the cerebellum ?

Answer 1

Via the pontine nuclei.

Question 2

Which part of the cerebral cortex project to the CB ?

Answer 2

Every lobe except the occipital one.

Question 3

Name the subdivisions that compose the CB.

Answer 3

Lobe - Lobules - Folia

Question 4

Which are the two main part of the CB ?

Answer 4

The cerebellar cortex and the cerebellar nucleus.

Question 5

Name the nuclei of the CB.

Answer 5

Dentate
Globulose
Emboliform
Fastigial

Question 6

Which distinctions can we make to subdivise the CB ?

Answer 6

Longitudinal:
Vermis
Intermediate hemisphere
Lateral hemisphere

Transversal:
Anterior lobe
posterior lobe
flocculonodular lobe

Functionnal :
vestibulo-cerebellum
spino-cerebellum
cerebro-cerebellum

Question 7

Name and describe the layers of the cerebellum

Answer 7

Molecular layer: few cell bodies (mainly for interaction between dendrites and axons)
Purkinje cell layer*
Granule cell layer (small cells)

Question 8

Describe purkinje cells in the CB :

Answer 8

purkinje cell layer
Big neurons 
large 2D dendritic arbor
descending axon to deep nuclei
GABAergic (inhibitory)
Main output of the cerebellar cortex
not numerous but voluminous

Question 9

Describe purkinje cells in the CB :

Answer 9

Granule cell layer (small cells)
small cell body
shord dendrites at the lvl of punkinje
axon ascend vertically from the molecular layer
glutamatergic (excitatory)
interneurones 
synapse on Purkinje
numerous
main input of the CB

They form parallel fibers.

Question 10

Which adjective can we use to describe the organisation between granule cells and purkinje cells ?

Answer 10

They have an orthogonal organisation

Question 11

Describe golgi cells in the CB :

Answer 11

axon and body in granule layer
medium sized
dendrites in the molecular and the granule layer.
It’s an inhibitory neuron, the granule cells excite the Golgi cells which will in return, inhibited the granule cells.

Question 12

Describe the basket

Answer 12

Inhibitory
medium sized
interneurons
located between granule and purkinje layers
Dendrites in the molecular layer
receive excitatory input from the granule cells
they synapse onto the Purkinje cells.
Their axons will follow a row of Purkinje cells and form like a basket around the Purkinje cells body.

THEY STRONGLY INHIBIT PURKINJE CELLS ON THEIR CELL BODY
can inhibit multiple purkinje c

Question 13

Name the different type of neurons you can fin in the CB

Answer 13

Basket and stellate cells
punkinje
golgi
granular

Question 14

Is there a difference if the input came from cell body membrane or from the dendrites ?

Answer 14

The signal is not the same. Delay is shorter.

Question 15

Describe the stellate cells inside the CB.

Answer 15

Star shape
inhibit purkinje cells at the level of their dendrites
can inhibit 3-5 purkinje cells