The Cytoskeleton and Microtubules Flashcards

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1
Q

What is the cytoskeleton?

A

A network of protein fibres that extends throughout the cytoplasm in all eukaryotic cells.

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2
Q

What is the cytoskeleton attached to?

A

Membrane proteins as well as organelles.

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3
Q

What is the function of the cytoskeleton?

A

Gives mechanical support to the cell acting as scaffolding to maintain the shape of the cell.

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4
Q

What is the cytoskeleton involved in?

A

The movement of cellular components such as vesicles or chloroplasts. And is responsible for the movement of whole cells.

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5
Q

What are microtubules the polymers of?

A

A dimer made from a-tubulin and b-tubulin.

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6
Q

Describe the structure of a-tubulin and b-tubulin

A

They are soluble globular proteins

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7
Q

What is the diameter of a microtubule.

A

25 nm

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8
Q

What are the microtubules a component of?

A

The cytoskeleton

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9
Q

What does the length of the microtubules depend on?

A

The addition or the removal of tubulin at the ends.

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10
Q

Where do microtubules originate from?

A

The microtubule organising centre (MTOC)

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11
Q

What does the MTOC contain?

A

The centrosome

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12
Q

Where is the site of microtubule synthesis in animal cells?

A

The centrioles within the centrosome

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13
Q

What are spindle fibres made of?

A

Microtubule

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14
Q

What is disassembled to form the microtubules of the mitotic and meiotic spindles?

A

Cytoplasmic microtubules

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15
Q

What do microtubules attach to?

A

Proteins at the centromeres of chromatids.

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16
Q

What does microtubule severing do?

A

Separates the chromatids