Cell Cycle Flashcards

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1
Q

What does interphase consist of?

A

G1, S and G2 stages

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2
Q

What happens during G1?

A

The cell makes new proteins and copies of the organelles

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3
Q

What happens during the S phase?

A

DNA replication occurs

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4
Q

What happens during the G2 phase?

A

The cell makes more proteins and copies of organelles in preparation for mitosis

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5
Q

What does the M phase consist of?

A

Mitosis and cytokinesis

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6
Q

What happens during Prophase?

A

The chromosomes condense and become visible as two joined chromatids, spindle fibres attach to centromeres, nuclear membrane disintegrates.

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7
Q

What happens during metaphase?

A

Spindle fibres move chromosomes so they line up along the metaphase plate at the equator of the cell.

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8
Q

What happens during anaphase?

A

The spindle fibres pull the sister chromatids apart

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9
Q

What happens during telophase?

A

The separated chromosomes are pulled by the spindle fibres to opposite poles to form daughter nuclei. Chromosomes uncoil and the nuclear membrane is made again.

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10
Q

What happens during cytokinesis?

A

The membrane is pulled in by part of the cytoskeleton to divide the cytoplasm to form two daughter cells.

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11
Q

What needs to happen before the membrane is made in plant cells?

A

Plant cells have to form a middle lamellae and cell wall

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12
Q

What is the mitotic index of a sample?

A

The percentage of cells undergoing mitosis

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13
Q

What is the purpose of the checkpoints?

A

The prevent progress of a cell during the cell cycle if something is incorrect

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14
Q

Where are the checkpoints placed?

A

The end of G1, the end of G2 and during metaphase

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15
Q

What does the G1 checkpoint monitor and control?

A

Monitors cell size (ensures sufficient cell mass is present to form two daughter cells) and allows the cell to continue to the S stage.

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16
Q

What does the G2 checkpoint monitor and control?

A

Monitors the success of DNA replication (ensuring the two daughter cells receive a complete copy of DNA) controls entry to mitosis using MPF

17
Q

What does the M checkpoint monitor and control?

A

Monitors chromosome alignment, (ensuring one chromatid from each chromosome is received by each daughter cell). Controls entry to anaphase. It triggers the exit of mitosis and the start of cytokinesis.