Normal differentiation and abnormal division Flashcards

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1
Q

What are differentiated cells?

A

Cells that are specialised for specific functions

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2
Q

What are tissues?

A

A group of differentiated cells which have the same function

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3
Q

What are organs?

A

Groups of tissues

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4
Q

What are totipotent cells?

A

Cells which can differentiate into any other cell type.

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5
Q

Where can you find totipotent cells.

A

Meristematic cells in plants

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6
Q

What are the regions of cells that are specialised and can produce a restricted range of cell types.

A

Adult stem cells.

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7
Q

What is a pluripotent cell?

A

A cell which is capable of giving rise to several different cell types

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8
Q

What is special about embryonic stem cells?

A

They have the ability to differentiate into any cell type.

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9
Q

Why does the repressor molecule attach to the operator?

A

So the transcription enzyme can not read the structural gene

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10
Q

Which gene produces the repressor molecule?

A

The regulator gene?

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11
Q

What happens to the repressor molecule when lactose is present?

A

Repressor molecule attaches to the inducer

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12
Q

What is the result of an open operator

A

The transcription enzyme can read the structural gene and produce b-galactosidase

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13
Q

What type of proteins do proliferation genes produce?

A

Proteins which promote cell divisions when an external sign is received. Such as an open wound.

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14
Q

What are un-mutated proliferation genes known as?

A

Proto-oncogenes.

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15
Q

What do oncogenes give?

A

Proteins with abnormal shapes which stimulate excessive cell division even in the absence of an external signal.

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16
Q

Why can oncogenes be thought of as dominant alleles?

A

A mutation only has to occur in one gene of the pair.

17
Q

What do anti-proliferation genes produce?

A

Proteins which restrict cell division by operating at the cell cycle checkpoints

18
Q

Why do both copies of the anti-proliferation gene need to mutate before control of the cell cycle is lost and a tumour starts to form.

A

One functioning gene can still produce the protein to inhibit the cell cycle