The Cancerous Cell Flashcards
1
Q
What is contact inhibition?
A
Growth in an ordered fashion, lost in cancer
2
Q
Give 4 examples of a proto-oncogene
A
Growth factors
Growth factor receptors
Signal transducers
Nuclear proto-oncogenes and transcription factors
3
Q
What is retinoblastoma?
A
Caused by a mutation in a tumour suppressor gene
4
Q
What are virus oncogenes in HPV16?
A
E6 and E7
5
Q
What is associated with gastric cancer?
A
Helicobaccter pylori
6
Q
What is familial adenomatous polyposis?
A
Colon cancer, single gene disorder, truncations in APC protein
7
Q
what causes hereditary non-polyposis colon cancer?
A
Mutations in mis-match repair enzymes hMLH1 and hMSH2
