The brain, neurons, drugs and disease CM Flashcards

1
Q

The nervous system consists of two major subdivisions, , the ____ and the____nervous system

A
  1. central (CNS)

2. peripheral (PNS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

the____ consists of the brain and _____

A
  1. CNS

2. Spinal cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

the ____ consists of the spinal cord and cranial ____ outside of the CNS.

A
  1. PNS

2. nerves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

the principle cellular unit of the nervous system is the _____

A

neuron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how many neurons are there approximately in an ‘average’ brain?

A

100 billion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how many synaptic connections are there between the neurons in the brain? approx.

A

0.15 quadrillion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Labels of a neuron

A
Dendrite
Soma
Nucleus
Axon
Node of Ranvier
Myelin Sheath 
Schwann Cell
Axon terminal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ions are _____ that are important for determining the difference in _______ between the inside and outside that all cells need to ______

A
  1. Charged particles
  2. Electrical charge
  3. function
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

neurotransmitter _____ cross the synapse and ____ to _____ on the postsynaptic ______

A
  1. molecules
  2. bind
  3. receptors
  4. membrane
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

in the synapse, when neurotransmitter molecules bind to receptors, this causes….

A

ion channels to open in the postsynaptic neuron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

______ of ions causes changes in ____ of inside relative to outside of the neuron

A
  1. Influx/ Efflux

2. Voltage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

In the Axon hillock, the voltage changes _____ from point of origin

A

Spread away

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Whether action potential is generated depends on….

A

size of the voltage change reaching the axon hillock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

an action potential travels from the ______, along the length of the ____, to the _________

A
  1. Axon hillock
  2. Axon
  3. terminal buttons
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

______ provides electrical insulation of the neuron- prevents ‘cross talk’ across ____ and loss of ____

A
  1. Myelin
  2. neurons
  3. signal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Myelin speeds up the _____ of the AP, it effectively jumps from one ________ to the next.

A
  1. relay

2. Node of Ranvier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

As long as the ____ travels from one end of the axon to the other, no information is lost in ________

A
  1. Action potential

2. Conduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the neurolemma?

A

A thin plasma membrane surrounding the neuron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

when the neuron is at rest, what charge does the inside of the neurolemma have?

A

negative charge

20
Q

What is the Resting Membrane Potential (RMP)?

A

the charge inside the neurolemma

21
Q

What is the RMP amount?

22
Q

What is the neuron when it has a RMP of -70mV?

23
Q

the AP is a wave of__________ that travels along the axon

A

depolarisation

24
Q

Particles carrying an electrical charge =

25
___________ of the neurolemma
Selective permeability
26
___________ of ions along concentration gradient
Passive diffusion
27
attraction/repulsion of charges=
Electrostatic pressure
28
_______ of ions across neurolemma
Active Transport
29
What does Active transport do?
it uses energy to transport ions against concentration gradient
30
ATP
Adenosine Triphosphate
31
ADP
Adenosine Diphosphate
32
What are sodium ions when the neuron is at rest?
More highly concentrated on the outside of the neuron
33
the membrane is fairly ______ to sodium ions
impermeable
34
_______ and ______ forces push sodium ions into the neuron when it is at rest, a few 'leak' into the neuron
1. Electrostatic | 2. Diffusion
35
What are potassium ions when the neuron is at rest?
more highly concentrated on the inside of the neuron
36
the membrane is fairly_______ to potassium ions
permeable
37
A little 'net' _____ force push potassium ions out of the neuron, causing a small 'leak'.
diffusion
38
What are chlorine ions when the neuron is at rest?
more highly concentrated on the outside of the neuron
39
the membrane is fairly______ to chlorine ions
permeable
40
______ and _______ forces roughly _____ out chlorine ions
1. Electrostatic 2. Diffusion 3. Balance
41
there is little _____ at rest for chlorine ions
movement
42
Big negatively charged ______ ions are stuck ____ the ion
1. Protein | 2. Inside
43
Protein ions contribute a lot to the resting ___________ of the inside of the neuron
negative charge
44
the membrane potential is a balancing act of _______ and ____________
1. membrane permeability | 2. ion concentrations
45
Disrupting the balance of membrane permeability and ion concentration in a neuron can initiate an ______
action potential
46
neurotransmitters change...
membrane permeability