The Blood clotting Cascade Flashcards
What substances are released when platelets break open
Serotonin, Thromboplastin
What is serotonin
Causes the smooth muscle of the blood vessel to contract. This narrows the blood vessels, cutting off the blood flow to the damaged area
What is thromboplastin
Enzyme that sets in progress a cascade of events that leads to the formation of a clot
The blood clotting cascade 1/4
Platelets form a plug and release clotting factors including thromplastin
The blood clotting cascade 2/4
Prothrombin is changed to its active form thrombin, catalysed by thromplastin
The blood clotting cascade 3/4
Thrombin acts on soluble fibrogen converting it to insoluble fibrin. This forms a mesh to cover the wound
the blood clotting cascaded 4/4
Platelets and blood cells become trapped in the fibrin mesh forming a blood clot and a scab
The blood clotting cascade 5/5
Calcium and vitamin K is essentially required for the progression and acceleration for the blood coagulation process
What is a platelet
cell fragement that releases thromplastin
What is thrombin
enzyme that changes fibrongen into fibrin
What is fibrogen
solubale plasma protein