The Anterior Pituitary Flashcards
Which epithelial tissue is the anterior pituitary made of
Glandular epithelial
Anterior pituitary also known as
Adenohypophysis
How do ant. Pituitary and hypothalamus communicate
Hypophyseal portal system
Hormones of adenohypophysis
GH
ACTH
LH
TSH
FSH
Prolactin
GH effects
AA uptake and PRO synthesis
Enhances fat utilization for energy
Decreases CHO utilization
Increases insulin secretion
Stimulates cartilage and bone growth through osteoblasts
GH released in response to
GHRH
First 2 hrs of sleep
Stimulation of GH
Decreased blood glucose
Decreased blood ffa
Starvation or fasting
Trauma stress
Exercise
Testosterone
Deep sleep
GHRH
Inhibition of GH
Increased blood glucose
Increased ffa
Obesity
Aging
Somatomedins
Somatostatin
GH causes liver to release
Insulin like growth factors
Most important IGF
IGF 1 or somatomedin C
MTOR pathway
Autophagy
Totipotent makes
Pluripotent
Pluripotent makes
Multipotent
Role of somatomedin C
Protein synthesis
Spares protein degradation
Overall muscle mass
What causes gigantism
High HG in childhood
What causes acromegaly
High HG post childhood
Dwarfism is a deficiency of what
Somadomedin C
When does circadian rhythm develop
3 months
How does the hypothalamus control the onset of sleep
GABA
NREM
Light stage, muscle tone present
NREM2
Deeper sleep, memory consolidation, HR and body temp drop, teeth grind
NREM3
Deepest sleep, body repairs
REM
Dreaming
90 mins after sleep begins
Irregular muscle movements
Increased brain O2, increased BP
Where is prolactin produced
Lactotroph cells in the anterior pituitary
