Glucose Homeostasis Flashcards

1
Q

Fasting blood glucose range

A

70-80 to 100-110 mg/dl

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2
Q

Time frame for sugar to enter the body
Simple sugar

A

10-15 mins

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3
Q

Time frame for sugar to enter the body
Whole grains

A

2+ hrs

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4
Q

Time frame for sugar to enter the body
Potatoes

A

1hr

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5
Q

Time frame for sugar to enter the body
White bread

A

2hrs

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6
Q

Time frame for sugar to enter the body
Whole grain bread

A

3-4 hrs

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7
Q

Glycemic response

A

Effect food has on blood glucose concentrations

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8
Q

Glycemic index

A

Classification of dietary carbs impact on glucose level

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9
Q

Glycemic load

A

Glycemic index times grams of carb in the meal

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10
Q

Glycemic index rapid digestion

A

High GI

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11
Q

Glycemic index slow digestion

A

Low GI

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12
Q

Where does pancreas connect

A

Duodenum

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13
Q

B cell

A

Insulin

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14
Q

A cell

A

Glucagon

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15
Q

D cell

A

Somatostatin

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16
Q

Pancreatic acini

A

Digestive enzymes

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17
Q

Hyperglycaemia stimulates

A

Beta cells to release insulin
Delta cells to release somatostatin

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18
Q

Hypoglycemia stimulates

A

Alpha cells to release glucagon

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19
Q

What type of hormone is insulin

A

Peptide hormone

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20
Q

What kind of bond does insulin have

A

Disulfide bond

21
Q

GLUT for muscle and adipose

22
Q

Insulin in the liver

A

Glycogenesis
Glycolysis
FA synthesis TAG
Cholesterol synthesis

23
Q

Insulin in adipose tissue

A

GLUT 4 transporter and glucose enters the cell
TAG storage

24
Q

Insulin in muscle cell

A

Stimulates GLUT 4 transporter and glucose enters cell
Glycogenesis
Glycolysis
Krebs
ETC

25
Somatostatin on hypothalamus
Decreases GHRH
26
Somatostatin on anterior pituitary
Decreased the release of GH
27
Somatostatin affects neurotransmitter and cell proliferation via
GPCR
28
Somatostatin on glucagon and insulin
Inhibitory
29
Glucagon on the liver
Glycogenolysis Gluconeogenesis B ox
30
Glucagon on adipose
Lipolysis
31
Hypoglycemia and acute stress
Stimulates the release of epinephrine from adrenal medulla
32
Hypoglycemia and sleep or exercise
Stimulates GHRH from hypothalamus
33
Fasting pre diabetic levels
100-125
34
Fasting diabetic
125+
35
What is A1c level
Representation of glucose adhered to blood cells in the past weeks
36
Normal A1c level
Less than 5.6
37
Prediabetic A1c level
5.7 to. 6.4%
38
Diabetic A1c level
Greater than 6.4%
39
Where does glucose attach to the RBC
Beta chain
40
Type 1 diabetes
Body’s immune systems attacks beta cells causing them to lose the ability to make insulin
41
Type 2 diabetes
Target cells lose the ability to respond normally to insulin
42
Type 2 diabetes
Target cells lose the ability to respond normally to insulin
43
Pre diabetes
High blood glucose
44
Gestational diabetes
Type 2 High blood glucose during pregnancy
45
Hypoglycemia
Low blood sugar resulting from excess insulin
46
When does reactive Hypoglycemia happen
After CHO rich food
47
When does fasting Hypoglycemia happen
Body produces too much insulin even when no food is eaten
48
Management of diabetes
Diet Physical activity Medications such as insulin
49
Hypothetical type 3 diabetes
Alzheimer’s