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PHY 6210 - Systems Phys > Final Exam > Flashcards

Final Exam Flashcards

1
Q

Dihydropyridine receptor location

A

Transverse tubule

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2
Q

Ryanodine receptor location

A

B/w DHP and SR

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3
Q

Ryanodine receptor function

A

Open SR and let’s Ca++ out

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4
Q

How is Ca++ so concentrated in the SR

A

Calsequestrin

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5
Q

What brings RMP to TP

A

End plate potential

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6
Q

Receptor type on skeletal muscle cell

A

Nicotinic

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7
Q

Skeletal - ATP bound to myosin

A

Detached until hydrolysis

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8
Q

Skeletal - release of Pi

A

Power stroke, actin is pulled medial

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9
Q

Zone between the actin filaments of the same sarcomere

A

H zone

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10
Q

Contraction - H zone

A

Disappears

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11
Q

Contraction - A band

A

No movement

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12
Q

PRO holding myosin to z disc

A

Titin

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13
Q

PRO holding thin filaments

A

Nebulin

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14
Q

Contraction - I band

A

Decreases

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15
Q

Z disc of smooth muscle

A

Dense bodies

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16
Q

Smooth - unitary muscle connected by what

A

Gap junctions

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17
Q

What is varicosity

A

Vesicle that can release different chemicals

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18
Q

Smooth muscle pace maker cells

A

Interstitial cells of cajal

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19
Q

Smooth - slow wave due to ____ and is ____ affected by hormones or nervous

A

Sodium, negatively

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20
Q

Smooth muscle GPro coupled receptor pathway

A

Phospholipase C to PIP2 to IP3

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21
Q

Smooth muscle calcium channels opened by

A

Nervous
Hormonal
Stretch

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22
Q

What stimulates MLCK

A

Calcium calmodulin complex

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23
Q

Purpose of MLCK

A

Adding Pi

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24
Q

Relaxation of smooth muscle requires

A

MLCP

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25
MLCP function
Removes Pi from myosin, ca++ leaves calmodulin
26
Cardiac muscle stimulus for release of Ca++
CACR
27
Sumbmucosal plexus also called
Meisseners
28
Myenteric plexus also called
Auerbachs
29
Vago vagal reflex
Vagus afferents (80%) and activate vagus efferent (20%) to innervate submucosal plexus
30
Oocyte name after fertilized and implanted
Blastocyst
31
Fetal vitamin C and Iron use
Intercellular substances bone matrix, need C to prevent anemia
32
Fetal calcium and vitamin d
Bone growth, need D for calcium
33
Is peristalsis sympathetic?
No
34
Activation of peristaltic reflex
Food in pharynx controlled by brain stem
35
Stimuli that initiate peristalsis
Distension of gut Irritation of gut epithelium Parasympathetic nervous system
36
Describe peristaltic contractions
Local intermittent constrictive contractions, 5-30 sec
37
Upper esophagus is what lower esophagus is what
Striated, smooth
38
Slow wave regulation of SI
Interstitial cells of cajal
39
Digestive enzymes made by pancreas
Trypsinogen, chymotrypsinogen, protelase, procarboxyleotidase
40
Chief cells make
Pepsinogen
41
Parietal cells make
HCL and intrinsic factor
42
Salivary amylase breaks down what
Carbs or disaccharides such as lactose, maltose, sucrose
43
Myenteric plexus stimulation
Increases tonic contraction Increased contraction frequency Increased propulsion
44
Myenteric inhibition
Decreased sphincter tone
45
Myenteric plexus function
GI motility
46
Brunners glands release
Bicarbonate
47
What causes CCK release
Fats and AA in duodenum
48
What inhibits stomach emptying
Cck Secretin GIP
49
Enzyme for smooth muscle
Myosin light chain kinase
50
Synthesis of ach
Acetyl coa and choline
51
Resting potential determined by
K
52
First part of the AP due to
Na in
53
Falling phase of AP due to
K leaving
54
Preganglioinic fibers pass through
White rami
55
Sweat glands and arrector pilorum innervated by
Cholinergic postganglionic sympathetic
56
Type of cholinergic receptor found at synapses between preganglionic and postganglionic neurons of symp
Nicotinic
57
What activates adrenergic alpha and beta equally
Epinephrine
58
Nasal lacrimal salivary and GI stimulated by what substance
Ach
59
What organ or system is sympathetic
Systemic blood vessels
60
What decreases in length in the sarcomere
I band
61
Best attribute to describe visceral smooth muscle
Contracts when stretched
62
Calmodulin relates to
Troponin c
63
Smooth muscle is terminated when
Dephosphorylation of myosin light chain
64
Delayed smooth muscle contraction due to
Slower cycling of smooth muscle myosin cross bridges

PHY 6210 - Systems Phys (8 decks)

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