Tetracyclines Flashcards

1
Q

Tetracyclines target what part of bacteria?

A

The 30s subunit of the ribosome

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2
Q

Tetracycline has how many rings?

A

4

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3
Q

Tetracyclines should not be used in what patient populations?

A

Children and pregnant women

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4
Q

Tetracyclines typically cover what types of bacteria

A

Gram (+) including VRE and MRSA; anaerobes; gram (-) except pseudomonas and decreased effectiveness for proteus and providencia

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5
Q

The niche application of tetracyclines is

A

Chlamydia, mycoplasma, spirochetes, rickettsia

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6
Q

Side effects of the tetracyclines include

A

Stained teeth, Ca2+ inactivation (also AL, FE, ZN), photosensitivity, and esophagitis, N/V

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