End Questions

Question 1

A 32-year-old male with a history of intravenous drug use presents to the ER with fever and chills. On physical exam, you note a fever and a holosystolic murmur along the right sternal border. Chest X-ray reveals multiple nodular lesions (some cavitating). Echocardiography confirms the presence of tricuspid valve endocarditis. Blood cultures initially grow out Staph Aureus. Sensitivities are pending so you start antibiotic A and continue/change to antibiotic B when the sensitivity comes back as methicilin sensitive.

What are antibiotics A and B?

Answer 1

Vancomycin; Nafcillin

Question 2

A 70-year-old female with bronchiectasis presents with a chronic cough which is green in nature despite 7 days of levofloxacin.

Which of the following cephalosporins is most likely to treat this patient?

Answer 2

Cefepime

Question 3

A 75-year-old woman on prednisone for polymyalgia rheumatica presented with a urinary tract infection two weeks ago for which she was treated with an antibiotic. She now complains of pain in her ankle and cannot walk.

What is the most likely antibiotic that she was prescribed?

Answer 3

Levofloxacin

Question 4

Name the TWO antibiotics that cover atypical bacteria in pneumonia by inhibiting ribosomes.
Tetracycline
Azithromycin
Vancomycin
Levofloxacin

Answer 4

Tetracycline & Azithromycin

Question 5

All of the following antibiotics inhibit ribosomes EXCEPT:
Clarithromycin
Meropenem
Minocycline
Gentamicin

Answer 5

Meropenem

Question 6

A 40-year-old cystic fibrosis patient is being treated for a lung infection.

Which of the following would NOT be a good choice of antibiotic?
Imipenem
Meropenem
Ertapenem
Piperacillin/tazobactam

Answer 6

Ertapenem

Question 7

A 65-year-old patient is diagnosed with an MRSA cellulitis. The patient is switched to linezolid because the MIC is = 2 for vancomycin.

What blood test should be routinely monitored?

Answer 7

CBC

Question 8

Which of the following medications can increase creatinine concentrations without necessarily worsening actual GFR?
TMP/SMX
Levofloxacin
Penicillin
Meropenem

Answer 8

TMP/SMX

Question 9

Which antibiotic covers both anaerobes and has a high propensity to cause Clostridium difficile colitis?

Answer 9

Clindamycin

Question 10

A patient has a ventricular fibrillation arrest while in the hospital and is transferred to the ICU after successful resuscitation while being treated for pneumonia.

Which of the following antibiotics should be discontinued and alternatives considered?
Meropenem
Piperacillin/tazobactam
Levofloxacin
TMP/SMX

Answer 10

Levofloxacin