Macrolides Flashcards
1
Q
The mechanism of action of macrolides is the targeting of
A
The 50s subunit of the ribosome
2
Q
Macrolides are _____.
A
Bacteriostatic
3
Q
What type of bacteria are typically covered by macrolides that are not covered by penicillins?
A
Atypical bacteria (legionella, mycoplasma, chlamydia)
4
Q
What do macrolides and fluoroquinolones have in common?
A
Both may prolong the QTc interval
5
Q
Macrolides accumulate in body tissues, allowing for what?
A
Longer interval dosing while remaining effective
6
Q
What macrolide typically has the most GI effects?
A
Erythromycin
7
Q
Hypoglycemia is a side effect associated with which macrolide?
A
Clarithromycin
