testicular cancer

Question 1

What are the clinical features of testicular cancer?

Answer 1

1. painless, firm lump - dull ache in the gorin
2. history of trauma
3. back pain - par oartic lymphnode mets
4. breathlessness - lung mets
5. bone pain - bone mets

Question 2

Describe the main pathology of testicular cancer?

Answer 2

1. 95% are germ cell tumours
   - seminomas (common in older men) (40%)

• non seminomas (younger men) (60%)

Question 3

name some examples of non seminoma testicular cancer?

Answer 3

1. teratoma / yolk cell carcinoma

Question 4

Ix of testicular cancer

Answer 4

1. ultra sound scan
2. tumor markers
3. CT scan of chest/abdo/pelvis for staging

Question 5

Name 3 main tumor markers

Answer 5

1. alpha fetoprotein
2. Beta HCG
3. lactate dehydrogenase

Question 6

main method of mx

Answer 6

1. radical bilateral orchidectomy

Question 7

Ajuvant tx - stage 1/2

Answer 7

adjuvant radiotherapy to para aortic nodes

Question 8

Adjuvant tx - stage 3/4

Answer 8

adjuvant radiotherapy with chemotherapy

Question 9

prognosis of testicular cancer

Answer 9

1. v v good

2. 5 year prognosis - 100% without mets and 95% with mets