prostate cancer Flashcards

1
Q

what are the symptoms of prostate cancer?

A
  1. LUTS
  2. bone pain
  3. family history
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2
Q

Examinations

A
  1. DRE

2. palpable bladder

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3
Q

Ix

A
  1. prostate specific antigen
  2. USS and biopsy
  3. CT/MRI for bone scanning
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4
Q

how is diagnosis made?

A

indic if raised psa/DRE

  1. Prostate biopsy
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5
Q

when is PSA elevated?

A

(PSA <4 normally)

  1. prostititis
  2. UTI
  3. Catheter
  4. Urinary retention
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6
Q

what is the classification system called?

A

Gleason grading

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7
Q

T1 - T2 meaning

A

organ confined cancer

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8
Q

T3 - T4

A

locally advanced cancer

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9
Q

N0-3

A

lymph node spread

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10
Q

M0-M1

A

absence or presence of distant metastasis

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11
Q

what are the 3 potential methods of mx?

A
  1. active surveillance
    ( if low life expectancy or slow growing tumor)
  2. surgery
    - prostatectomy
  3. radiotherapy
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12
Q

mx of metastatic prostate cancer?

A

Hormonal manipulation therapy - Androgen deprivation therapy

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13
Q

Mx of low risk Prostate cancer?

A
  1. active surveillance

2. RP/RT

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14
Q

Mx of intermediate risk Prostate cancer?

A
  1. RP/RT

2. adjunct hormonal manipulationn

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15
Q

Mx of high risk Prostate cancer?

A
  1. RP/RT

2. ADT for up to 3 years -can slow down disease progression

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16
Q

Name 3 examples of ADT?

A
  1. Leutenising hormone releasing hormone antagonists

2. bilateral orchidectomy