Test Prep Flashcards

1
Q

quinine antimalaria drug causes oxidative stress which causes jaundice in patients with ______

A

G6PD deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Gastrectomy commonly causes

A

Vitamin B12 deficiency due to inability to absorb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Heparin-induced thrombocytopenia causes

A

inappropriate clotting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Renal disease causes anemia due to ______

A

Decreased production of EPO (erythropoetin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

hyperbilirubinemia is the same as

A

jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

P53 mutation inhibits

A

P21 formation, causes proliferation of tumors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cancer is immortal because of _____

A

increased telomerase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Thabdomyosarcoma comes from:

A

Skeletal muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Iron is recycled in the______

A

bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Vitamin B12 lab result:

A

Increased MCV, macrocytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

blood clotting factors synthesized in

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

cirrhosis causes

A

decreased levels of fibrinogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cancer cells evade

A

apoptosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

chronic liver failure causes:

A

thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Decreased bile salt impairs gut absorption of

A

vitamin K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hemoglobin S

A

sickle cell

17
Q

sickle cell

A

heterozygotes (carriers) - trait

homozygotes (full manifestation) - disease

18
Q

primary source of billirubin

A

heme from RBC recycling

19
Q

conjugated bilirubin

A

liver conjugates and then body can secrete

20
Q

hydrophobic amnio acid replaces hydrophilic amino acid

A

sickle cell

21
Q

genetic tests for Breast cancer

A

BRCA 1 and 2
HER2
ER (estrogen receptor)

22
Q

hemolytic anemia causes:

A

jaundice

23
Q

hypoxic uterine leads to

A

Increased RBC