blood disorders

Question 1

percent of blood made up of RBC

Answer 1

hematocrit

Question 2

amount of protein in a volume of blood

Answer 2

hemoglobin

Question 3

normal hemoglobin for women

Answer 3

11-15 g/dL

Question 4

Normal hemoglobin for men

Answer 4

14-18 g/dL

Question 5

normal hematocrit for men

Answer 5

39-54%

Question 6

normal hematocrit for women

Answer 6

34-47%

Question 7

appearance of cells in vitamin B12/folate anemia

Answer 7

macrocytic, hypochromic

Question 8

Required for myelin formation

Answer 8

vitamin B12

Question 9

neurologic findings may be irreversible

Answer 9

vitamin B12 anemia

Question 10

Hemolytic anemia indicator:

RBC, hematocrit, hemoglobin

Answer 10

Decreased

Question 11

hemolytic anemia indicator:

MCV

Answer 11

may be stable but RDW increases

Question 12

reticulocyte count in hemolytic anemia

Answer 12

increased

Question 13

blood smear of hemolytic anemia

Answer 13

schistocytes

Question 14

increased iron and lactate dehydrogenase

Answer 14

hemolytic anemia

Question 15

bilirubin is increased in _____

Answer 15

hemolytic anemia

Question 16

Genetic disorder/RBCs have inadequate protection from oxidative stress

Answer 16

Glucose-6-phosphate dhehydrogenase deficiency (G6PD)

Question 17

Fava beans exacerbate ____

Answer 17

G6PD deficiency

Question 18

explain why fava beans exacerbate G6PD deficiency

Answer 18

damage RBC integrity and increase hemolysis due to oxidization

Question 19

antibodies bind to RBC

Answer 19

autoimmune hemolytic anemia

Question 20

often seen with SLE

Answer 20

Autoimmune hemolytic anemia

Question 21

How does. thalassemia differ from iron deficiency anemia

Answer 21

thalassemia is genetic mutation of A or B hemoglobin chains

Question 22

key component of hemostasis

Answer 22

rapid clot formation in a region of injury while suppressing clot extension beyond that region.

Question 23

catalyst for intravascular clot formation

Answer 23

endothelial injury

Question 24

most common bleeding disorder
autosomal dominant
heterogeneous

Answer 24

von willebrand disease

Question 25

vicohows triad: favor pathological clot formation (nontrauma)

Answer 25

endothelial injury
venous stasis
hypercoagulability

Question 26

von willebrand disease: genetic manifestation

Answer 26

autosomal dominant
incomplete penetrance
may have genotype without phenotype

Question 27

Von Willebrand disease findings

Answer 27

mucosal bleeding, epistaxis, excessive childhood bruising, menorrhagia