Test 4 Flashcards
The flu shot is an example of:
A. Natural passive immunity
B. Natural Active immunity
C. Artificial Passive Immunity
D. Artificial Active Immunity
D. Artificial Active Immunity
A breastfed infant is an example of :
A. Natural Passive Immunity
B. Natural Active Immunity
C. Artificial passive immunity
D. Artificial active immunity
A. Natural passive immunity
An infection of immunoglobulin such as an anti-venom or RhoGAM would be:
A. Natural passive immune
B. Natural active immune
C. Artificial passive immune
D. Artificial active immune
C. Artificial passive immune
Which of the following R’s does not refer to the body’s ability to be immune?
A.recognize
B.remember
C.react
D.retard
D.retard
When multiple B cells produce antibodies against antigens on the same pathogen it is referred to as a:
A. Poly wants cracker
B. Polyester suit
C. Polyclonal response
C. Polyclonal response
Which complement component has 2 jobs?
A. C3b
B. C3a
C. C2a
D. C4b
E. None of these
A. C3b
What are 2 jobs of the component in question #15?
Opsonization and inflammation
List the components responsible for :
A. Opsinization
B. Inflammation
C. Lysis
A. Opsinization-C3b
B. Inflammation- C2b, C3a, C4a, C5a
C. Lysis-C5b, C6, C7, C8, C9
List the 3 complement activation pathways and their triggers?
Classical- antigens and antibodies complex bonds and active
Alternate- microbes bond with BDP factors
Lectin- microbes with mannose binding lectin
Give the antibody class responsible for the following examples of Natural Passive Immunity: fetus.
IgG
Give the antibody class responsible for the following examples of Natural Passive Immunity: breast-fed infant (general).
IgA
Give the antibody class responsible for the following examples of Natural Passive Immunity: breast-fed infant (when mother has an active immune response).
IgG
The basic structure of an antibody molecule includes:
- 2 heavy chains
- 2 _____chains
- _______bonds
- a _________region that determines the molecule’s class
- a ___________region that contains the antigen binding sites
- some classes also include a _________ fixation site
- Heavy chain
- Light chain
- Disulfide bonds
- Fe
- Fv binding
- Carbon (C)
List the 6 categories of non-specific defense and how they work.
- Physical barriers - works by blocking
- Chemical barriers - works by killing
- Special resistance - is somewhere they do not want to go
- Phagocytosis - identify what is foreign and go after
- Inflammation - serves to localize an infection or a site of tissue damage
What is the purpose of a vaccine?
To stimulate the immune system to recognize and combat pathogens by helping fight off or kill an disease or infection.
________is found on all nucleated body cells and identifies those cells to our immune system as being part of ‘self’.
[MHC 1]
______ is found on WBCs and is used for antigen recognition and presentation.
[MHC 2]
________ is a molecule too small to be recognized by the immune system by itself, but it can be recognized in conjunction with another molecule.
[Hapten]
_____ and _____ activate complement by binding C1.
[IgM, IgG]
Type _____ hypersensitivity involves cytotoxic T cells and can take one or two days to develop.
4
__________ chemicals released during inflammation serve as a 9-1-1 call to attract the ________ which serve as the body’s policemen.
[Chemokines, leukocytes]
Active type immunities are long term due to the formation of ___________________________ (which is specifically the programming of B cells against an antigen).
[memory cells]
A T-dependent antigen requires input from a ______ to activate the B cell when it is presented.
[helper T cell]
An activated B cell will divide into 2 types of daughter cells. A ________ which is a copy of the parent cell and will retain the IgD antibodies for all antigens the parent cell had been programmed for and _______ cells which are responsible for producing antibodies against the antigen which activated the parent cell.
[memory B cell, plasma B cells]
Which 2 inflammatory mediators are not in the Alternate pathway?
[C3a, C5a]
Lymphocytes which become sensitized to ‘self’ antigens are removed by ____________________, in tissues such as the thymus.
[colonal deletion ]
Which type of repair results in scar formation?
[Stromal repair]
Give 3 Specific Examples of Integrated Defense
Phagocyte present process to b-cells
Inflammatory mediators tiggers inflammation
Inflammation tiggers endogenous pyrogens which tiggers a fever
The antibody class associated with allergic reactions. Fill in the blank: _____
E
The only class that can cross the placental barrier. Fill in the blank: _____
G
The class involved with Immune Complex hypersensitivity. Fill in the blank: _____
G
The class found on the surface of B lymphocytes. Fill in the blank: _____
D
The class that can exist as a dimer. Fill in the blank: _____
A
The class that exists as a pentamer. Fill in the blank: _____
M
The class secreted onto mucosal surfaces and in exocrine gland secretions. Fill in the blank: _____
A
The class produced first in a secondary immune response. Fill in the blank: _____
G
The class bound to the surface of MAST cells and basophils. Fill in the blank: _____
E
