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Pharmacology I > TEST 3 - ANTINEOPLASTIC DRUGS - DEFINITIONS > Flashcards

TEST 3 - ANTINEOPLASTIC DRUGS - DEFINITIONS Flashcards

1
Q

Uncontrolled and rapid cellular growth

A

CANCER

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2
Q

Grow & invade adjacent tissues

A

CANCER CELLS

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3
Q

Break away from original tumor mass and travel by means of the blood or lymphatic system to distant sites

A

CANCER CELLS

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4
Q

is a disease or symptom that is the consequence of the presence of cancer in the body?

A

PARANEOPLASTIC SYNDROMES (PNS)

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5
Q

WHAT ARE THE First Sign of Malignancy:

A

o Cachexia (most common) – like wasting
o Fever, fatigue, weight loss
o Others

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6
Q

WHAT IS THE Pharmacological treatment of cancer?

A

CHEMOTHERAPY

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7
Q

Uses Antineoplastic drugs (like anticancer)

2 groups of antineoplastic drugs (based on where they work in the cellular life cycle)
 Cell cycle-nonspecific (CCNS)
 Cell cycle-specific (CCS)
o Some drugs have characteristics of both

A

CHEMOTHERAPY

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8
Q

TRUE OR FALSE

Does Antineoplastic drugs differentiate between healthy and non-cancerous cells

A

FALSE

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9
Q

Original site of growth

A

PRIMARY LESION

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10
Q
  • Uncontrolled cell growth

* Secondary lesion in a new part of the body

A

METASTASIS

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11
Q

Mass of new cells; tumor

A

NEOPLASM

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12
Q

can be benign or malignant (cancerous)

A

TUMOR

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13
Q

cancers of epithelial tissue

A

CARCINOMAS

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14
Q

cancers of connective tissue

A

SARCOMA

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15
Q

cancers of bone marrow, lymph tissue

A

LYMPHOMAS

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16
Q

cancer cancers of blood

A

LEUKEMIAS

17
Q

Non-cancerous and not an immediate threat to life.

A

BENIGN

18
Q

Leakage of an intravenously or intra-arterially administered drug into the tissue space surrounding the blood vessel.

A

EXTRAVASATION

19
Q

The absence of cellular differentiation

A

ANAPLASIA

20
Q

A malignant neoplasm of blood-forming tissues.

A

LEUKEMIA

21
Q

A neoplasm of lymphoid tissue that is usually malignant but, in rare cases, may be benign

A

LYMPHOMA

22
Q

The process by which cancer spreads from the original site of growth to a new and remote part of the body.

A

METASTASIS

23
Q

Antineoplastic drugs that are cytotoxic in any phase of the cellular growth cycle.

A

CELL-CYCLE NON-SPECIFIC

24
Q

A malignant neoplasm of the connective tissue arising in fibrous, fatty, muscular, synovial, vascular, or neural tissue.

A

SARCOMA

25
Q

A permanent change in cellular genetic material (DNA).

A

MUTATION

26
Q

An alkylating agent.

A

CYCLOPHOSPHAMIDE

27
Q

A cytotoxic antibiotic.

A

BLEOMYCIN

28
Q

An antimetabolite.

A

METHOTREXATE

29
Q

A mitotic inhibitor.

A

VINCRISTINE

30
Q

A radiopharmaceutical.

A

SODIUM IODIDE I-131

31
Q

The lowest point in a fluctuating value.

A

NADIR

Pharmacology I (13 decks)

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