LA 2 Flashcards
What is the purpose of a “drug holiday” with clients who are taking narcotics on a long-term basis?
With narcotics, especially stronger agents, that are used long-term (e.g., ms contin, transdermyl fentanyl), a 3-day drug holiday (or as ordered by the physician) every month has shown evidence of increasing the sensitivity of the client to specific narcotics, as now the receptors have also become more sensitive.
true or false and explain your answer:
Cancer clients should never receive strong narcotics at the beginning of any pain experience because of the fear of addiction
False. With cancer pain, a client’s quality of life is far more important than the fear of addiction. Clients who are living with cancer need to experience comfort and maintain quality of life as much as possible. Addiction should not even be a concern for these clients because quality of life is so important for those afflicted with the illness.
You administer 100 mg meperidine (Demerol) intramuscularly to a client in severe post-operative pain, as ordered. What assessment data should be gathered before and after administering this drug? Explain your answer.
The nurse should always assess the client’s blood pressure, pulse, and respirations before administering any narcotic or, in this situation, meperidine. This allows comparison of baseline vital signs to those taken after the drug has been administered, as well as the assessment of the effect of the drug on the physiological response to pain.
Your client complains that the drugs he is receiving for severe pain are really not helping. What should be the most appropriate response to this client?
- First, it is important to assess the client and his or her previous reactions to pain medications and then assess the dose, action, route, and appropriateness of the agent.
- The client’s medical history, nursing assessment, and medication history should also be studied carefully because the client’s diagnosis may not match up with the type of analgesic ordered.
- Once it has been determined that the client is getting the right medication and dosage, then education about pain management
- The nurse should administer the medication at regular intervals, as ordered
- The nurse should also always include non-pharmacological methods of pain management
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of self-preparation:
Oral:
Very easy if alert; easy to teach others.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of self-preparation:
IM:
Not easy to carry out on own; would need assistance from healthcare personnel or other trained person
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of self-preparation:
Transdermal
Easy to learn to use and easy to teach to others.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of administration:
Oral:
Very easy if alert; easy to teach others.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of administration:
IM:
Easy to administer medication by this route if qualified healthcare provider is there to assist
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of administration:
Transdermal
Easy to administer and learn how to apply. Very easy to instruct on application and administration of patch.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Onset of therapeutic effects:
Oral:
Varies depending on specific drug properties and chemical composition of the oral drug; some very predictable and some very unpredictable. Generally speaking, 45 minutes to 1 hour for onset of effects. Remember that some drugs with longer half-lives may take weeks to have therapeutic effects
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting
Onset of therapeutic effects:
IM
Generally dependable; onset of therapeutic effects within at least 15 to 30 minutes
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Onset of therapeutic effects:
Transdermal
Dependable onset but is variable in some of the pharmacokinetics until serum steady states are achieved because of the nature of topical absorption into systemic circulation. However, once used for a few days, transdermal patches are very effective in their onset of therapeutic effects.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Serum concentrations:
Oral
Serum concentrations are dependent on the drug, its properties, chemical composition and dosage form (i.e., if enteric-coated. If the oral drug is taken at regular intervals, it may achieve adequate serum concentrations; however, many physiological factors provide barriers to predictable concentrations of the drug in the serum.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Serum concentrations:
IM
Very effective serum concentrations.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Serum concentrations:
Transdermal
Very effective serum concentrations that remain fairly predictable with routine usage and application.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Degree of sedation:
Oral:
Degree of sedation is dependent on dosage of drug and the potency of the drug. Medications such as morphine and other opioid derivatives are very sedating, but again, level of sedation depends on dose and other variables.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Degree of sedation:
IM
: Once again, the degree of sedation depends on drug and dosage, but because systemic absorption is more rapid, there are more CNS-depressing effects, and thus more CNS sedation
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Degree of sedation:
Transdermal
CNS sedation depends on drug patch and dosage. Often the client builds up some resistance to the sedation, but this is generally seen with lower dosage forms of the patch.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Side-effects:
Oral:
Narcotics usually have many side effects, and even more with oral dosage forms owing to gastric upset related to gastric irritation.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Side-effects:
IM
Side effects depend on drug and dosage but with IM route, the effects are generally more profound because of increased absorption. Therefore, the side effects related to CNS depression, such as sedation and decreased vital signs, are more often associated with these dosage forms.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Side-effects:
•Transdermal
Side effects are very likely to occur with transdermal patches once the steady state of the drug is achieved. Because of steady absorption with consistent dosing, the side effects will depend on the dosage and drug.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of home management:
Oral
Very easy.
Compare and contrast the effectiveness of oral, intramuscular, and transdermal routes for narcotic administration, considering ease of self-preparation and administration, onset of therapeutic serum concentrations, degree of sedation, side effects, and ease of management in the home setting.
Ease of home management:
IM
Not easy without medical or nursing assistance.