Test 3 Flashcards
What are the three major regions of the skin ?
- Epidermis
- Dermis
- Hypodermis aka Subcutaneous layer (Sub-Q)
Epidermis
- Outer layer
- Thinner layer
- Epithelial tissue
- 5 layers (stratum basale, stratum spinosum, stratum granulosum, stratum lucidum & stratum corneum)
Dermis
- Inner Layer
- Thicker layer
Hypodermis aka Subcutaneous (Sub-Q) Layer
- Located underneath the dermis
- Loose areolar/adipose connective tissue
- Attaches the skin to the underlying tissues and organs
Difference between keratinocytes and melanocytes
Keratinocytes and melanocytes are cells in the epidermis
Keratinocytes
- 90% of cells that make up the epidermis
secrete keratin, a tough protein that gives the skin and the hair its health
Melanocytes
- secrete melanin which is responsible for pigment
What are the five layers of the epidermis and what happens in each layer?
Bring Something Good Like Corn (mnemonic device)
(From deepest to most superficial)
Stratum Basale (Bring)
-Deepest level
-Continuous cell division
Stratum Spinosum (Something)
-8 to 10 layers of keratinocytes
Stratum Granulosum (Good)
-Layer where there are granules filled with keratin that secrete the keratinocytes
-Remember, as we go from the deepest layer to the most superficial level we end up with dead layers of skin
Stratum Lucidum (Like)
- Clear layer that you only see in thick skin (fingertips, palms, and soles)
- (Clear = lucid)
Stratum Corneum (Corn)
- 15 to 20 layers of dead keratinocytes
- Continuously shed and are replaced by cells from deeper strata
What are the 2 layers that make up the dermis?
Papillary and reticular
Eccrine glands
- Majority of sweat glands, most of the sweat we secrete
- found on palms, hands, soles of feet, and forehead
Apocrine glands
-Activated after puberty (Stinky)
- Found in groin, anogenital region, armpits, areola of breasts
What are sebaceous glands?
- Oil glands
- Sebum inhibits the growth of bacteria by preventing bacteria from entering your skin
What is the arrector pili muscle?
- Muscle responsible for giving you goosebumps
- Found attached to hair follicles in the dermis
What are the functions of the integumentary system?
- Protection
- Synthesis of vitamin D
-Regulation of body temperature (negative feedback - temp goes up - you sweat - cools down the body)
Basal cell carcinoma
Most common skin cancer
The likelihood that it metastasizes is very slim, Usually easily treated
Squamous cell carcinoma
Second most common skin cancer
Similar to basal cell
It can metastasize but it takes a lot , chances are slim
Malignant melanoma
- Least common
- Most Dangerous
- Likely to spread and metastasize to the brain and the bone, different areas of the body
ABCD Rule: of Melanoma
A for asymmetry, not symmetrical
B for border, no defined border
C for color, color is weird looking, black, reddish, orange
D for diameter, larger than 5 or 6 mm is considered significant
1st degree burn
affects the epidermis
2nd degree burn
affects the epidermis and the dermis
Partial thickness burn
Blister formation
3rd degree burn
- affects epidermis, dermis and hypodermis
- Full thickness burn
- Burn out the receptors that sensitize pain
- Skin graft is needed
- Infection can occur
Vitiligo
- depigmented patches of skin
- cause is unknown
- autoimmune in nature
Albinism
- Complete or partial absence of pigment in skin, hair and eyes
- Defective enzyme that makes melanin
- Serious condition
- Can cause blindness
Hyaline Cartilage
Most Abundant
Ribs, nose, trachea
found in bone, it lines the joints and caps the ends of the bones
Fibrocartilage
Discs of the knee and of the back
Elastic Cartilage
- External ear
Long bone
Humerus, femur, tibia, fibula, ulna, radius, metacarpals, metatarsals, and phalanges
Short bone
(cubed shaped)
Carpals and tarsals
Irregular Bone
Vertebrae
Sesamoid bone
(protect tendons from excessive wear)
Patella
Flat bone
Sternum, skull, ribs, scapula, clavicles
Functions of bone
- Provide support (structural support/ framework)
- Protect internal organs
- Assist body movements
- Stores and releases constituents of bone like calcium and phosphorus
- Participates in blood cell production (hematopoiesis)
- Stores triglycerides in adipose cells (fat) of yellow marrow