Test 3 Flashcards
Functions of Cell Membrane
Boundary between ICF and ECF
-Contains contents of cell or “what is cell vs. what is not”
-Controls what passing in/out
-Role in Structural Support
-Establish Membrane Protentional
-Separate ions
-Inside cell = more negative.
Majority of Membrane is…
98% lipid
75% of that is Phospholipid
Plasma membrane is made of…
Parts:
-Phospholipid
-Membrane Proteins
Phospholipid is made of…
Glycerol
Phosphate head
Fatty Acid Tail
Phospholipid bilayer
Fluid mosaic model
Cholesterol
Glycerol
Linking portion(molecule) of the head
Phosphate head
Charge Present, making it hydrophilic
The top of the head, part with the charge.
Fatty Acid Tail
Chains of Hydrocarbons
Hydrophobic/lipid soluble
Phospholipid Bilayer
Phosphate Head-Toward ECG/ICF
Hydrophobic tail region is sandwiched between the phosphate heads
Maximizes Hydrophobic/philic interactions
Organization of molecules prevents hydrophilic molecules from easily crossing the membrane.
Cell membrane can self seal punctures/use vesicle blebbing/formation to pinch off.
Fluid Mosaic Model
Phospholipids and other molecules embedded in the membrane are able to laterally shift.
Cholesterol
-27 carbon, 4 ring structure, is a lipid
-fills gaps within middle of phosphate bi layer
-Permeable to water
- Less gaps=less water sneaking through
-Fluidity
-reduced ability for phospholipids to shift around.
Membrane Proteins
Structure: Integral-Embedded in membrane(all the way through)
Peripheral-Not embedded all the way through
Function of Membrane Proteins
Anchoring proteins-stabilize cell/Attach C.M. to other structures
Transport proteins-Channels/pumps(ATP/ASC)
receptors-bind and respond ligand
enzymes-catalyze chemical reactions
recognition-self cell vs. foeign cells.
Cell membrane physiology
Selectively permeable
-Semi Permeable
-Regulates what can and cant come through
What can come through?
Lipophilic molecules
Usually Water
(w/out help) large hydrophilic molecules
Ion(tiny hydrophilic atoms aren’t able to cross)
What is movement restricted on?
Size, electrical charge, Molecule shape, lipid solubility.
Why are cells small?
Cell size is limited by surface area
What happens as cell size increases
Surface area increases, volume increases
Why does it’s SA increase
Need more surface area because increase in materials that cross
Why does volume increase
Increase in metabolism, increase in distance
Therefore…
-As cell size increases, there needs to be proportional to or greater than the increase in cell volume
-Cell size is limited to manageable size, Increased organism size due to increase cell number
What are the 2 ways to move across a membrane?
Active/Passive Transport
Passive Process
Diffusion, Osmosis, and Facilitated Diffusion
Diffusion
Random Movement of a substance from a high concentration to a low concentration
Brownian Movement (diffusion)
Molecules are in constant movement, random due to thermal energy.
Solute
Any substance dissolved in a solution
Solvent
What stuff is dissolved in
Simple Diffusion
Moment of particles down a concentration gradient
Why isn’t simple diffusion in living systems
Gradients need to be healthy, energy input to move particles, and conditions are always changing.
Osmosis
Diffusion of water across membrane
Tonicity
Relative solute concentrations of 2 fluids
Predicts H2O movements.
Osmotic Pressure
Pulling pressure due to non-diffusible solutes
Isotonic Solution
Same solute concentration
No net movement of H2O
Hypertonic Solution
Higher Solute Concentration (Lower H20 Concentration)
Hypotonic Solution
Lower Solute concentration (Higher H20 Concentration)
Hydrostatic Pressure
Pushing pressure due to the volume of H2O
Equilibrium
No Net movement of H2O
Osmotic Pressure is equal and opposite to hydrostatic pressure.
Hypotonic vs. Hypertonic vs. Isotonic
Net movement of H2O in, Net movement out, and net movement out and in.
Crenation
Cells shrink, net movement of H2O is out
Hemolysis
Red blood cells burst with H2O
Passive Transport-Facilitated Diffusion
Faster than simple diffusion, Protein mediated transport, Requires no ATP. Particles go down the concertation gradient.
Active Transport
Movement against the concentration gradient. Protein Mediated, requires ATP
Vesicular Transport
Transport involves vesicles, Requires ATP, Pinching off or merging of membrane.
Exocytosis vs Endocytosis
The moment of particles out vs in through Vesicular transport.
Functions of the Nervous System
Communication/Coordination, Sensory, Integration, Motor
Components of the Nervous System
CNS(Brain/Spinal Cord) vs PNS(All nerves outside the CNS.
Components of peripheral NS
Sensory(Afferent/carry info toward CNS) and Motor(Efferent/carry info away from CNS)
Components of the Afferent division of PNS
Special Sensory(senses), Somatic Sensory(skin/muscles), Visceral Sensory(smooth/cardiac muscle).
Components of the Peripheral nervous system
Somatic Motor(carry from sensory to effectors, voluntary, skeletal muscle), Autonomic Nervous System
Autonomic Nervous system
Involuntary(Cardiac, smooth, glands). Encompasses the Enteric, Sympathetic, and Parasympathetic systems
Enteric N.S.
G.I Tract(gut)-secretions and mailability
Sympathetic N.S.
Stimulating effect, stress response, uses norepinephrine
Parasympathetic N.S
Relaxing Effect, Rest and Repair, counter balances SNS. Uses Aceytlcholine
Cell Types of N.S.
Neurons/Neuroglia
Neuroglia
Support Cells, Surround Neurons, Non-excitable, more sophisticated you are, more neuroglia
Characteristics of Neurons
Longevity, Amitotic(no cell division), High Metabolic rate(constant o2 and glucose), Excitable to then become conductive of electric impulses, secretory
Myelinated Axons
Bundles of neuron Processes
Tract Vs. Nerve
CNS vs. PNS
Unmyelinated structure of Neuron
groups of cell bodies