Test 3 Flashcards
Functions of Cell Membrane
Boundary between ICF and ECF
-Contains contents of cell or “what is cell vs. what is not”
-Controls what passing in/out
-Role in Structural Support
-Establish Membrane Protentional
-Separate ions
-Inside cell = more negative.
Majority of Membrane is…
98% lipid
75% of that is Phospholipid
Plasma membrane is made of…
Parts:
-Phospholipid
-Membrane Proteins
Phospholipid is made of…
Glycerol
Phosphate head
Fatty Acid Tail
Phospholipid bilayer
Fluid mosaic model
Cholesterol
Glycerol
Linking portion(molecule) of the head
Phosphate head
Charge Present, making it hydrophilic
The top of the head, part with the charge.
Fatty Acid Tail
Chains of Hydrocarbons
Hydrophobic/lipid soluble
Phospholipid Bilayer
Phosphate Head-Toward ECG/ICF
Hydrophobic tail region is sandwiched between the phosphate heads
Maximizes Hydrophobic/philic interactions
Organization of molecules prevents hydrophilic molecules from easily crossing the membrane.
Cell membrane can self seal punctures/use vesicle blebbing/formation to pinch off.
Fluid Mosaic Model
Phospholipids and other molecules embedded in the membrane are able to laterally shift.
Cholesterol
-27 carbon, 4 ring structure, is a lipid
-fills gaps within middle of phosphate bi layer
-Permeable to water
- Less gaps=less water sneaking through
-Fluidity
-reduced ability for phospholipids to shift around.
Membrane Proteins
Structure: Integral-Embedded in membrane(all the way through)
Peripheral-Not embedded all the way through
Function of Membrane Proteins
Anchoring proteins-stabilize cell/Attach C.M. to other structures
Transport proteins-Channels/pumps(ATP/ASC)
receptors-bind and respond ligand
enzymes-catalyze chemical reactions
recognition-self cell vs. foeign cells.
Cell membrane physiology
Selectively permeable
-Semi Permeable
-Regulates what can and cant come through
What can come through?
Lipophilic molecules
Usually Water
(w/out help) large hydrophilic molecules
Ion(tiny hydrophilic atoms aren’t able to cross)
What is movement restricted on?
Size, electrical charge, Molecule shape, lipid solubility.
Why are cells small?
Cell size is limited by surface area
What happens as cell size increases
Surface area increases, volume increases
Why does it’s SA increase
Need more surface area because increase in materials that cross
Why does volume increase
Increase in metabolism, increase in distance
Therefore…
-As cell size increases, there needs to be proportional to or greater than the increase in cell volume
-Cell size is limited to manageable size, Increased organism size due to increase cell number
What are the 2 ways to move across a membrane?
Active/Passive Transport
Passive Process
Diffusion, Osmosis, and Facilitated Diffusion
Diffusion
Random Movement of a substance from a high concentration to a low concentration
Brownian Movement (diffusion)
Molecules are in constant movement, random due to thermal energy.